Methyl cis-6-chloro-2-hexenoate

Base Information

• Chemical Name: Methyl cis-6-chloro-2-hexenoate
• CAS No.: 152668-34-3
• Molecular Formula: C₇H₁₁ClO₂
• Molecular Weight: 162.616
• Mol file: 152668-34-3.mol

Synonyms:Methyl cis-6-chloro-2-hexenoate

Chemical Property of Methyl cis-6-chloro-2-hexenoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl cis-6-chloro-2-hexenoate

There total 1 articles about Methyl cis-6-chloro-2-hexenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-chlorobutyraldehyde (6139-84-0) + methyl (diphenoxyphosphoryl)acetate (219617-17-1) → Methyl cis-6-chloro-2-hexenoate (152668-34-3)

Guidance literature:

at -90 ℃; for 2h;

DOI:10.1002/ejoc.200700965

Reference yield:

Methyl cis-6-chloro-2-hexenoate (152668-34-3) → endo-Tricyclo<6.2.1.02,7>-8-undecen-2-one (51519-65-4,115795-03-4,115795-04-5,127062-97-9,127062-98-0,127708-33-2)

Guidance literature:

Multi-step reaction with 3 steps

1: Et₂AlCl / toluene / 50 °C

2: NaI / acetone / 12 h / Heating

3: 83 percent / SmI₂ / iron(III)tris(dibenzoylmethane) / tetrahydrofuran / 0.5 h

With samarium diiodide; diethylaluminium chloride; sodium iodide; tris(dibenzoylmethano)iron(III); In tetrahydrofuran; acetone; toluene;

DOI:10.1021/jo00077a053

Reference yield:

2,3-dimethyl-buta-1,3-diene (513-81-5) + Methyl cis-6-chloro-2-hexenoate (152668-34-3) → (1R,6S)-6-(3-Chloro-propyl)-3,4-dimethyl-cyclohex-3-enecarboxylic acid methyl ester

Guidance literature:

With diethylaluminium chloride; In toluene; at 50 ℃;

DOI:10.1021/jo00077a053

upstream raw materials:

4-chlorobutyraldehyde

methyl (diphenoxyphosphoryl)acetate

Downstream raw materials:

endo-Tricyclo<6.2.1.0^2,7>-8-undecen-2-one