3-(4-fluorophenyl)-5,6-dihydro-6-oxo-1(4H)-pyridazineacetic acid methyl ester

Base Information

Chemical Name:3-(4-fluorophenyl)-5,6-dihydro-6-oxo-1(4H)-pyridazineacetic acid methyl ester
CAS No.:142731-42-8
Molecular Formula:C₁₃H₁₃FN₂O₃
Molecular Weight:264.256
Hs Code.:

Synonyms:3-(4-fluorophenyl)-5,6-dihydro-6-oxo-1(4H)-pyridazineacetic acid methyl ester

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Chemical Property of 3-(4-fluorophenyl)-5,6-dihydro-6-oxo-1(4H)-pyridazineacetic acid methyl ester

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Technology Process of 3-(4-fluorophenyl)-5,6-dihydro-6-oxo-1(4H)-pyridazineacetic acid methyl ester

There total 2 articles about 3-(4-fluorophenyl)-5,6-dihydro-6-oxo-1(4H)-pyridazineacetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 366-77-8
4-(4-fluorophenyl)-4-oxopropionic acid

: 142731-42-8
3-(4-fluorophenyl)-5,6-dihydro-6-oxo-1(4H)-pyridazineacetic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / hydrazine hydrate / ethanol / 17 h / Heating

2: 1) NaH / 1) THF, room temp., 30 min; 2) THF, room temp., 17 h

With sodium hydride; hydrazine hydrate; In ethanol;