39499-62-2

Basic information

• Product Name: 6-(4-FLUOROPHENYL)-4,5-DIHYDRO-3(2H)-PYRIDAZINONE
• Synonyms: 6-(4-FLUOROPHENYL)-4,5-DIHYDRO-3(2H)-PYRIDAZINONE;6-(4-FLUOROPHENYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE
• CAS NO: 39499-62-2
• Molecular Formula: C₁₀H₉FN₂O
• Molecular Weight: 192.19
• Mol File: 39499-62-2.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-(4-FLUOROPHENYL)-4,5-DIHYDRO-3(2H)-PYRIDAZINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-FLUOROPHENYL)-4,5-DIHYDRO-3(2H)-PYRIDAZINONE(39499-62-2)
• EPA Substance Registry System: 6-(4-FLUOROPHENYL)-4,5-DIHYDRO-3(2H)-PYRIDAZINONE(39499-62-2)

Safety Data

• Hazardous Substances Data: 39499-62-2(Hazardous Substances Data)

Upstream product

• 366-77-8 4-(4-fluorophenyl)-4-oxopropionic acid 
• 39560-31-1 methyl 3-(4-fluorobenzoyl)-propionate 
• 459-57-4 4-fluorobenzaldehyde 
• 462-06-6 fluorobenzene 

Downstream Products

• 117826-24-1 6-[4(2-Amino-ethoxy)-phenyl]-4,5-dihydro-2H-pyridazin-3-one 
• 1444311-56-1 2-[3-(4-fluorophenyl)-5-(3-methoxybenzyl)-6-oxopyridazin-1(6H)-yl]acetic acid 
• 1444311-55-0 2-[3-(4-fluorophenyl)-5-(4-methoxybenzyl)-6-oxopyridazin-1(6H)-yl]acetic acid 
• 1444311-40-3 ethyl 2-[3-(4-fluorophenyl)-5-(3-methoxybenzyl)-6-oxopyridazin-1(6H)-yl]acetate 
• 1444311-39-0 ethyl 2-[3-(4-fluorophenyl)-5-(4-methoxybenzyl)-6-oxopyridazin-1(6H)-yl]acetate 
• 690956-41-3 6-(4-fluorophenyl)-4-(4-methoxybenzyl)pyridazin-3(2H)-one 
• 1444311-24-3 6-(4-fluorophenyl)-4-(3-methoxybenzyl)pyridazin-3(2H)-one 
• 66548-52-5 3-chloro-6-(4-fluorophenyl)pyridazine 
• 66548-73-0 6-(4-fluoro-phenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazine 
• 66548-51-4 6-(p-fluorophenyl)-1,2,4-triazolo[4,3-b)pyridazine 
• 142731-50-8 2-[3-(4-Fluoro-phenyl)-6-oxo-5,6-dihydro-4H-pyridazin-1-yl]-N-isopropyl-acetamide 
• 142731-51-9 3-(4-fluorophenyl)-5,6-dihydro-N-(1,1-dimethylethyl)-6-oxo-1(4H)-pyridazineacetamide 
• 142731-49-5 3-(4-fluorophenyl)-5,6-dihydro-N-ethyl-6-oxo-1(4H)-pyridazineacetamide 

Relevant articles and documents

Synthesis, molecular modeling of novel substituted pyridazinones and their vasorelaxant activities

Background: Hypertension, one of the most common cardiovascular diseases that can cause coronary disease, stroke, myocardial infarction, and sudden death, it is the major contributor to cardiac failure as well as renal insufficiency. Objectives: As there

DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS

Compounds of formula I: I are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disorders in a patient in need are also disclosed. Such disorders include depression, bipolar disorder, pain, schizophrenia, obsessive compulsive disorder, addiction, social disorder, attention deficit hyperactivity disorder, an anxiety disorder, autism, a cognitive impairment, or a neuropsychiatric symptom such as apathy, depression, anxiety, psychosis, aggression, agitation, impulse control disorders, and sleep disorders in neurological disorders such as Alzheimer's and Parkinson's diseases.

Further studies on 2-arylacetamide pyridazin-3(2H)-ones: Design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists

Formyl peptide receptors (FPRs) play an essential role in the regulation of endogenous inflammation and immunity. In the present studies, a large series of pyridazin-3(2H)-one derivatives bearing an arylacetamide chain at position 2 was synthesized and te