1,3,3-trimethyl-2-methylene-5-nitrobenzoylamino-6-nitroindoline

Base Information

• Chemical Name: 1,3,3-trimethyl-2-methylene-5-nitrobenzoylamino-6-nitroindoline
• CAS No.: 133478-01-0
• Molecular Formula: C₁₉H₁₈N₄O₅
• Molecular Weight: 382.376
• Mol file: 133478-01-0.mol

Synonyms:1,3,3-trimethyl-2-methylene-5-nitrobenzoylamino-6-nitroindoline

Chemical Property of 1,3,3-trimethyl-2-methylene-5-nitrobenzoylamino-6-nitroindoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3,3-trimethyl-2-methylene-5-nitrobenzoylamino-6-nitroindoline

There total 3 articles about 1,3,3-trimethyl-2-methylene-5-nitrobenzoylamino-6-nitroindoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

1,3,3-trimethyl-2-methylene-5-benzoylaminoindoline (133478-00-9) → 1,3,3-trimethyl-2-methylene-5-nitrobenzoylamino-6-nitroindoline (133478-01-0)

Guidance literature:

With sulfuric acid; nitric acid; at 20 ℃; for 48h;

DOI:10.1007/BF00476978

Reference yield:

benzoyl chloride (98-88-4) → 1,3,3-trimethyl-2-methylene-5-nitrobenzoylamino-6-nitroindoline (133478-01-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / triethylamine / CH₂Cl₂ / 24 h / 20 °C

2: 68 percent / HNO₃, conc. H₂SO₄ / 48 h / 20 °C

With sulfuric acid; nitric acid; triethylamine; In dichloromethane;

DOI:10.1007/BF00476978

Reference yield:

5-amino-1,3,3-trimethyl-2-methylene-indoline (6872-05-5) → 1,3,3-trimethyl-2-methylene-5-nitrobenzoylamino-6-nitroindoline (133478-01-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / triethylamine / CH₂Cl₂ / 24 h / 20 °C

2: 68 percent / HNO₃, conc. H₂SO₄ / 48 h / 20 °C

With sulfuric acid; nitric acid; triethylamine; In dichloromethane;

DOI:10.1007/BF00476978

upstream raw materials:

1,3,3-trimethyl-2-methylene-5-benzoylaminoindoline

benzoyl chloride

5-amino-1,3,3-trimethyl-2-methylene-indoline