6-Phenylimidazo(2,1-b)-1,3,4-thiadiazole-2-sulfonamide

Base Information

Chemical Name:6-Phenylimidazo(2,1-b)-1,3,4-thiadiazole-2-sulfonamide
CAS No.:63735-71-7
Molecular Formula:C₁₀H₈N₄O₂S₂
Molecular Weight:280.331
Hs Code.:
UNII:7EZF1A283N
DSSTox Substance ID:DTXSID80213176
Wikidata:Q27195229
ChEMBL ID:CHEMBL19231

Synonyms:AEG 3482;AEG-3482;AEG3482

Suppliers and Price of 6-Phenylimidazo(2,1-b)-1,3,4-thiadiazole-2-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
AEG 3482
10mg
$ 389.00

TRC
AEG 3482
5mg
$ 495.00

Tocris
AEG 3482 ≥99%(HPLC)
50
$ 599.00

Tocris
AEG 3482 ≥99%(HPLC)
10
$ 147.00

Sigma-Aldrich
AEG 3482 ≥98% (HPLC)
25mg
$ 439.00

Sigma-Aldrich
AEG 3482 ≥98% (HPLC)
5mg
$ 109.00

Cayman Chemical
AEG 3482
25mg
$ 339.00

Cayman Chemical
AEG 3482
1mg
$ 28.00

Cayman Chemical
AEG 3482
10mg
$ 150.00

Cayman Chemical
AEG 3482
5mg
$ 89.00

Total 14 raw suppliers

Chemical Property of 6-Phenylimidazo(2,1-b)-1,3,4-thiadiazole-2-sulfonamide

Chemical Property:

PKA:5.05±0.60(Predicted)
Density:1.75
Storage Temp.:Store at RT
Solubility.:DMSO: ≥15mg/mL
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:280.00886786
Heavy Atom Count:18
Complexity:405

Purity/Quality:

97% ^*data from raw suppliers

AEG 3482 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CN3C(=N2)SC(=N3)S(=O)(=O)N
Uses AEG 3482 is an antiapoptotic compound that inhibits Jun Kinase Activity (JNK) and cell death through induced expression of heat shock protein 70. AEG 3482 shows possible use in the treatment of neurological disorders.

Technology Process of 6-Phenylimidazo(2,1-b)-1,3,4-thiadiazole-2-sulfonamide

There total 2 articles about 6-Phenylimidazo(2,1-b)-1,3,4-thiadiazole-2-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%