toluene-4-sulfonic acid 2-(2-cyclohexyk-5-methyloxazol-4-yl)ethyl ester

Base Information

• Chemical Name: toluene-4-sulfonic acid 2-(2-cyclohexyk-5-methyloxazol-4-yl)ethyl ester
• CAS No.: 401791-03-5
• Molecular Formula: C₁₉H₂₅NO₄S
• Molecular Weight: 363.478

Synonyms:toluene-4-sulfonic acid 2-(2-cyclohexyk-5-methyloxazol-4-yl)ethyl ester

Chemical Property of toluene-4-sulfonic acid 2-(2-cyclohexyk-5-methyloxazol-4-yl)ethyl ester

Chemical Property:

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Technology Process of toluene-4-sulfonic acid 2-(2-cyclohexyk-5-methyloxazol-4-yl)ethyl ester

There total 2 articles about toluene-4-sulfonic acid 2-(2-cyclohexyk-5-methyloxazol-4-yl)ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

4-dimethylamino pyridine (DMAP) + 2-(2-cyclohexyl-5-methyl-oxazol-4-yl)-ethanol (132646-47-0) → toluene-4-sulfonic acid 2-(2-cyclohexyk-5-methyloxazol-4-yl)ethyl ester (401791-03-5)

Guidance literature:

With pyridine; In dichloromethane;

Reference yield:

→ toluene-4-sulfonic acid 2-(2-cyclohexyk-5-methyloxazol-4-yl)ethyl ester (401791-03-5)

Guidance literature:

Reference yield: 48.0%

3-(4-Hydroxy-phenyl)-2-methyl-2-(quinolin-6-yloxy)-propionic Acid Ethyl Ester (401791-48-8) + toluene-4-sulfonic acid 2-(2-cyclohexyk-5-methyloxazol-4-yl)ethyl ester (401791-03-5) → 3-{4-[2-(2-Cyclohexyl-5-methyl-oxazol-4-yl)-ethoxy]-phenyl}-2-methyl-2-(quinolin-6-yloxy)-propionic Acid (401790-88-3)

Guidance literature:

With hydrogenchloride; sodium hydroxide; potassium carbonate; In ethanol; dichloromethane;

upstream raw materials:

2-(2-cyclohexyl-5-methyl-oxazol-4-yl)-ethanol

Downstream raw materials:

2-[1-{4-[2-(2-Cyclohexyl-5-methyl-oxazol-4-yl)-ethoxy]-phenyl}-meth-(E)-ylidene]-4-(3aR,7aS)-octahydro-isoindol-2-yl-4-oxo-butyric acid ethyl ester

2-Methyl-3-(4-{2-[5-methyl-2-cyclohexyl-oxazol-4-yl]-ethoxy}-phenyl)-2-phenoxypropionic Acid Ethyl Ester

3-{4-[2-(2-Cyclohexyl-5-methyloxazol-4-yl)-ethoxy]-3-methoxyphenyl}-2-methyl-2-phenoxypropionic Acid

2-Methyl-3-(4-{2-[5-methyl-2-cyclohexylyl-oxazol-4-yl]-ethoxy}-phenyl)-2-(4-tert-butylphenoxy)-propionic Acid

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