(E)-1-methyl-4-(2-phenylethenyl)-1,2,3,6-tetrahydropyridine N-oxide

Base Information

• Chemical Name: (E)-1-methyl-4-(2-phenylethenyl)-1,2,3,6-tetrahydropyridine N-oxide
• CAS No.: 143888-17-9
• Molecular Formula: C₁₄H₁₇NO
• Molecular Weight: 215.295
• Mol file: 143888-17-9.mol

Synonyms:(E)-1-methyl-4-(2-phenylethenyl)-1,2,3,6-tetrahydropyridine N-oxide

Chemical Property of (E)-1-methyl-4-(2-phenylethenyl)-1,2,3,6-tetrahydropyridine N-oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1-methyl-4-(2-phenylethenyl)-1,2,3,6-tetrahydropyridine N-oxide

There total 2 articles about (E)-1-methyl-4-(2-phenylethenyl)-1,2,3,6-tetrahydropyridine N-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-1-methyl-4-(2-phenylethenyl)-1,2,3,6-tetrahydropyridine (130407-16-8) → (E)-1-methyl-4-(2-phenylethenyl)-1,2,3,6-tetrahydropyridine N-oxide (143888-17-9)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; at 0 ℃; for 1h;

DOI:10.1021/jm00100a023

Reference yield:

(E)-1-methyl-4-(2-phenylethenyl)pyridinium iodide (20111-34-6) → (E)-1-methyl-4-(2-phenylethenyl)-1,2,3,6-tetrahydropyridine N-oxide (143888-17-9)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄ / methanol / 0.5 h / Ambient temperature

2: 60percent m-CPBA / 1 h / 0 °C

With sodium tetrahydroborate; 3-chloro-benzenecarboperoxoic acid; In methanol;

DOI:10.1021/jm00100a023

Reference yield: 82.0%

(E)-1-methyl-4-(2-phenylethenyl)-1,2,3,6-tetrahydropyridine N-oxide (143888-17-9) → (E)-1-methyl-4-(2-phenylethenyl)-2,3-dihydropyridinium perchlorate

Guidance literature:

With perchloric acid; trifluoroacetic anhydride; In dichloromethane; at 0 ℃; for 1h;

DOI:10.1021/jm00100a023

upstream raw materials:

(E)-1-methyl-4-(2-phenylethenyl)-1,2,3,6-tetrahydropyridine

(E)-1-methyl-4-(2-phenylethenyl)pyridinium iodide