Ethyl 3,5-Dibromo-1-Methyl-1H-Pyrazole-4-Carboxylate

Base Information

Chemical Name:Ethyl 3,5-Dibromo-1-Methyl-1H-Pyrazole-4-Carboxylate
CAS No.:1017802-88-8
Molecular Formula:C₇H₈Br₂N₂O₂
Molecular Weight:311.961
Hs Code.:
Mol file:1017802-88-8.mol

Synonyms:3,5-dibromo-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester

Suppliers and Price of Ethyl 3,5-Dibromo-1-Methyl-1H-Pyrazole-4-Carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl3,5-Dibromo-1-methylpyrazole-4-carboxylate
10mg
$ 45.00

Crysdot
Ethyl3,5-dibromo-1-methyl-1H-pyrazole-4-carboxylate 95+%
1g
$ 416.00

Crysdot
Ethyl3,5-dibromo-1-methyl-1H-pyrazole-4-carboxylate 95+%
5g
$ 1250.00

ChemScene
Ethyl3,5-dibromo-1-methyl-1H-pyrazole-4-carboxylate
5g
$ 1238.00

ChemScene
Ethyl3,5-dibromo-1-methyl-1H-pyrazole-4-carboxylate
1g
$ 413.00

Total 9 raw suppliers

Chemical Property of Ethyl 3,5-Dibromo-1-Methyl-1H-Pyrazole-4-Carboxylate

Chemical Property:

Melting Point:69 °C
Boiling Point:334.5±37.0 °C(Predicted)
PKA:-3?+-.0.10(Predicted)
Density:1.95±0.1 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

Ethyl3,5-Dibromo-1-methylpyrazole-4-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Ethyl 3,5-Dibromo-1-methylpyrazole-4-carboxylate is used as a reactant in the synthesis of 3-amino-1,5-dihydro-4H-pyrazolopyridin-4-one derivatives as tyrosine kinase 2 inhibitors.

Technology Process of Ethyl 3,5-Dibromo-1-Methyl-1H-Pyrazole-4-Carboxylate

There total 2 articles about Ethyl 3,5-Dibromo-1-Methyl-1H-Pyrazole-4-Carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1017802-86-6
3,5-dibromo-1H-pyrazole-4-carboxylic acid ethyl ester

: 74-88-4
methyl iodide

: 1017802-88-8
3,5-dibromo-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 20 ℃;
DOI:10.1080/00397910701818578

Reference yield:

: 37622-90-5
4-ethoxycarbonylpyrazole

: 1017802-88-8
3,5-dibromo-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium acetate; bromine / ethanol; water / 10 h / 10 - 35 °C

2.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 °C / Inert atmosphere

2.2: 10 h / 0 - 35 °C / Inert atmosphere

With bromine; sodium acetate; sodium hydride; In tetrahydrofuran; ethanol; water; mineral oil;