3-(tetrahydropyran-4-yl)-2-[4-(tetrahydropyran-4-ylmethylsulfanyl)phenyl]-N-thiazol-2-ylpropionamide

Base Information

Chemical Name:3-(tetrahydropyran-4-yl)-2-[4-(tetrahydropyran-4-ylmethylsulfanyl)phenyl]-N-thiazol-2-ylpropionamide
CAS No.:745052-11-3
Molecular Formula:C₂₃H₃₀N₂O₃S₂
Molecular Weight:446.635
Hs Code.:

Synonyms:3-(tetrahydropyran-4-yl)-2-[4-(tetrahydropyran-4-ylmethylsulfanyl)phenyl]-N-thiazol-2-ylpropionamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(tetrahydropyran-4-yl)-2-[4-(tetrahydropyran-4-ylmethylsulfanyl)phenyl]-N-thiazol-2-ylpropionamide

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Technology Process of 3-(tetrahydropyran-4-yl)-2-[4-(tetrahydropyran-4-ylmethylsulfanyl)phenyl]-N-thiazol-2-ylpropionamide

There total 1 articles about 3-(tetrahydropyran-4-yl)-2-[4-(tetrahydropyran-4-ylmethylsulfanyl)phenyl]-N-thiazol-2-ylpropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 101691-94-5
4-(iodomethyl)tetrahydro-2H-pyran

: 2-(4-mercaptophenyl)-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylpropionamide

: 745052-11-3
3-(tetrahydropyran-4-yl)-2-[4-(tetrahydropyran-4-ylmethylsulfanyl)phenyl]-N-thiazol-2-ylpropionamide

Guidance literature:: With triethylamine; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 16h;

Reference yield:

: 745052-11-3
3-(tetrahydropyran-4-yl)-2-[4-(tetrahydropyran-4-ylmethylsulfanyl)phenyl]-N-thiazol-2-ylpropionamide

: 26272-83-3
oxetan-3-yl 4-methylbenzenesulfonate

: 745053-81-0
2-[4-(oxetan-3-ylsulfanyl)phenyl]-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylpropionamide

Guidance literature:: With potassium carbonate; sodium iodide; In N,N-dimethyl acetamide; at 130 ℃; for 2h;

Reference yield:

: 1120-90-7
3-iodopyridine

: 745052-11-3
3-(tetrahydropyran-4-yl)-2-[4-(tetrahydropyran-4-ylmethylsulfanyl)phenyl]-N-thiazol-2-ylpropionamide

: 745052-12-4
2-[4-(pyridin-3-ylsulfanyl)phenyl]-3-(tetrahydropyran-4-yl)-N-thiazol-2-ylpropionamide

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium tert-butylate; bis[2-(diphenylphosphino)phenyl] ether; In toluene; at 20 - 105 ℃; for 2.55h;