methyl 5-(2,4-diisobutoxy-5-nitrobenzoylamino)-2,4-dimethoxybenzoate

Base Information

• Chemical Name: methyl 5-(2,4-diisobutoxy-5-nitrobenzoylamino)-2,4-dimethoxybenzoate
• CAS No.: 915184-68-8
• Molecular Formula: C₂₅H₃₂N₂O₉
• Molecular Weight: 504.537
• Mol file: 915184-68-8.mol

Synonyms:methyl 5-(2,4-diisobutoxy-5-nitrobenzoylamino)-2,4-dimethoxybenzoate

Chemical Property of methyl 5-(2,4-diisobutoxy-5-nitrobenzoylamino)-2,4-dimethoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 5-(2,4-diisobutoxy-5-nitrobenzoylamino)-2,4-dimethoxybenzoate

There total 3 articles about methyl 5-(2,4-diisobutoxy-5-nitrobenzoylamino)-2,4-dimethoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-dimethoxy-5-nitro-benzoic acid methyl ester (81574-75-6) → methyl 5-(2,4-diisobutoxy-5-nitrobenzoylamino)-2,4-dimethoxybenzoate (915184-68-8)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd/C

2: 2.96 g / Et₃N / CH₂Cl₂ / 20 Torr

With hydrogen; triethylamine; palladium on activated charcoal; In dichloromethane;

DOI:10.1021/ol062103d

Reference yield:

2,4-diisobutoxy-5-nitro-benzoyl chloride + methyl 5-amino-2,4-dimethoxybenzoate (70752-22-6) → methyl 5-(2,4-diisobutoxy-5-nitrobenzoylamino)-2,4-dimethoxybenzoate (915184-68-8)

Guidance literature:

With triethylamine; In dichloromethane; under 20 Torr;

DOI:10.1021/ol062103d

Reference yield:

2,4-diisobutoxy-5-nitrobenzoic acid (874210-18-1) → methyl 5-(2,4-diisobutoxy-5-nitrobenzoylamino)-2,4-dimethoxybenzoate (915184-68-8)

Guidance literature:

Multi-step reaction with 2 steps

1: (COCl)2; DMF / CH₂Cl₂ / Heating

2: 2.96 g / Et₃N / CH₂Cl₂ / 20 Torr

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;

DOI:10.1021/ol062103d

upstream raw materials:

methyl 5-amino-2,4-dimethoxybenzoate

2,4-diisobutoxy-5-nitrobenzoic acid

2,4-dimethoxy-5-nitro-benzoic acid methyl ester

Downstream raw materials:

methyl 5-[5-(2,4-dimethoxy-benzylamino)-2,4-diisobutoxy-benzoylamino]-2,4-dimethoxybenzoate