Technology Process of C40H46F2N4O8
There total 5 articles about C40H46F2N4O8 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C34H35F2N3O7;
With
hydrogenchloride;
In
1,4-dioxane;
at 20 ℃;
for 1.75h;
N-tert-butyloxycarbonyl-L-tert-leucine;
With
N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
N,N-dimethyl-formamide;
Further stages.;
DOI:10.1016/j.bmc.2006.11.003
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 55 percent / HBTU; ethyldiisopropylamine / dimethylformamide / 20 °C
2.1: hydrochloric acid / dioxane / 1.75 h / 20 °C
2.2: 52 percent / HATU; ethyldiisopropylamine / dimethylformamide
With
hydrogenchloride; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2006.11.003
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 55 percent / HBTU; ethyldiisopropylamine / dimethylformamide / 20 °C
2.1: hydrochloric acid / dioxane / 1.75 h / 20 °C
2.2: 52 percent / HATU; ethyldiisopropylamine / dimethylformamide
With
hydrogenchloride; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2006.11.003
