3-(3-cyano-5-ethynyl-4-methoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole

Base Information

Chemical Name:3-(3-cyano-5-ethynyl-4-methoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole
CAS No.:1285574-69-7
Molecular Formula:C₁₈H₁₂N₂O₄S
Molecular Weight:352.37
Hs Code.:

Synonyms:3-(3-cyano-5-ethynyl-4-methoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole

Suppliers and Price of 3-(3-cyano-5-ethynyl-4-methoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(3-cyano-5-ethynyl-4-methoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(3-cyano-5-ethynyl-4-methoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole

There total 12 articles about 3-(3-cyano-5-ethynyl-4-methoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1285574-45-9
methyl 3-cyano-5-ethynyl-4-methoxybenzoate

: 1285574-69-7
3-(3-cyano-5-ethynyl-4-methoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole

Guidance literature:: Multi-step reaction with 4 steps

1: lithium hydroxide monohydrate; water / tetrahydrofuran / 3 h / 20 °C

2: oxalyl dichloride / N,N-dimethyl-formamide / toluene / 1.5 h / 20 °C / Cooling with ice

3: triethylamine / dichloromethane / 2.5 h / 20 °C

4: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 16 h / 20 °C

With oxalyl dichloride; lithium hydroxide monohydrate; water; triethylamine; 3-chloro-benzenecarboperoxoic acid; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane; toluene;

Reference yield:

: 1285574-64-2
3-cyano-5-ethynyl-4-methoxybenzoic acid

: 1285574-69-7
3-(3-cyano-5-ethynyl-4-methoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl dichloride / N,N-dimethyl-formamide / toluene / 1.5 h / 20 °C / Cooling with ice

2: triethylamine / dichloromethane / 2.5 h / 20 °C

3: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 16 h / 20 °C

With oxalyl dichloride; triethylamine; 3-chloro-benzenecarboperoxoic acid; N,N-dimethyl-formamide; In dichloromethane; toluene;

Reference yield:

: 156001-68-2
methyl 3-cyano-4-hydroxybenzoate

: 1285574-69-7
3-(3-cyano-5-ethynyl-4-methoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole

Guidance literature:: Multi-step reaction with 8 steps

1: N-iodo-succinimide; trifluorormethanesulfonic acid / methanol; chloroform / 1 h / 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 18 h / 20 °C

3: copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 1 h / 20 °C

4: water; sodium hydroxide / tetrahydrofuran / 0.17 h / 20 °C

5: lithium hydroxide monohydrate; water / tetrahydrofuran / 3 h / 20 °C

6: oxalyl dichloride / N,N-dimethyl-formamide / toluene / 1.5 h / 20 °C / Cooling with ice

7: triethylamine / dichloromethane / 2.5 h / 20 °C

8: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 16 h / 20 °C

With N-iodo-succinimide; oxalyl dichloride; lithium hydroxide monohydrate; trifluorormethanesulfonic acid; water; potassium carbonate; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium hydroxide; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; N,N-dimethyl-formamide; In tetrahydrofuran; methanol; dichloromethane; chloroform; N,N-dimethyl-formamide; toluene;