C₅₀H₄₈N₄O₂S₃

Base Information

• Chemical Name: C₅₀H₄₈N₄O₂S₃
• CAS No.: 1246814-42-5
• Molecular Formula: C₅₀H₄₈N₄O₂S₃
• Molecular Weight: 833.155
• Mol file: 1246814-42-5.mol

Synonyms:C₅₀H₄₈N₄O₂S₃

Chemical Property of C₅₀H₄₈N₄O₂S₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₀H₄₈N₄O₂S₃

There total 5 articles about C₅₀H₄₈N₄O₂S₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

C47H47N3OS3 (1246814-45-8) + cyanoacetic acid (372-09-8) → C50H48N4O2S3 (1246814-42-5)

Guidance literature:

With piperidine; In tetrahydrofuran; acetonitrile; for 8h; Reflux; Inert atmosphere;

DOI:10.1002/asia.201000158

Reference yield:

4,7-dibromobenzo[c][1,2,5]thiadiazole (15155-41-6) → C50H48N4O2S3 (1246814-42-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydroxide / tetrahydrofuran

2.1: trichlorophosphate / 1,2-dichloro-ethane / 12 h / 0 °C / Inert atmosphere; Reflux

2.2: 0.5 h

3.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / -5 - 20 °C / Inert atmosphere

4.1: piperidine / tetrahydrofuran; acetonitrile / 8 h / Reflux; Inert atmosphere

With piperidine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium tert-butylate; sodium hydroxide; trichlorophosphate; In tetrahydrofuran; 1,2-dichloro-ethane; acetonitrile; 1.1: Suzuki coupling / 2.1: Vilsmeier reaction / 2.2: Vilsmeier reaction / 3.1: Wittig reaction / 4.1: Knoevenagel reaction;

DOI:10.1002/asia.201000158

Reference yield:

sodium 4-hexyl-2-thienylboronate → C50H48N4O2S3 (1246814-42-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydroxide / tetrahydrofuran

2.1: trichlorophosphate / 1,2-dichloro-ethane / 12 h / 0 °C / Inert atmosphere; Reflux

2.2: 0.5 h

3.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / -5 - 20 °C / Inert atmosphere

4.1: piperidine / tetrahydrofuran; acetonitrile / 8 h / Reflux; Inert atmosphere

With piperidine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium tert-butylate; sodium hydroxide; trichlorophosphate; In tetrahydrofuran; 1,2-dichloro-ethane; acetonitrile; 1.1: Suzuki coupling / 2.1: Vilsmeier reaction / 2.2: Vilsmeier reaction / 3.1: Wittig reaction / 4.1: Knoevenagel reaction;

DOI:10.1002/asia.201000158

upstream raw materials:

5,5'-(2,1,3-benzothiadiazole-4,7-diyl)bis(3-hexylthiophene-2-carbaldehyde)

Diethyl (4-diphenylamino)benzyl phosphonate

C₄₇H₄₇N₃OS₃

cyanoacetic acid