dimethyl 2-(2-(pivalamido)phenyl)malonate

Base Information

• Chemical Name: dimethyl 2-(2-(pivalamido)phenyl)malonate
• CAS No.: 1452922-60-9
• Molecular Formula: C₁₆H₂₁NO₅
• Molecular Weight: 307.346
• Mol file: 1452922-60-9.mol

Synonyms:dimethyl 2-(2-(pivalamido)phenyl)malonate

Chemical Property of dimethyl 2-(2-(pivalamido)phenyl)malonate

Chemical Property:

Purity/Quality:

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Technology Process of dimethyl 2-(2-(pivalamido)phenyl)malonate

There total 2 articles about dimethyl 2-(2-(pivalamido)phenyl)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

dimethyl diazomalonate (6773-29-1) + N-pivaloylaniline (6625-74-7) → dimethyl 2-(2-(pivalamido)phenyl)malonate (1452922-60-9)

Guidance literature:

With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; silver(I) acetate; silver(I) triflimide; In 1,2-dichloro-ethane; at 90 ℃; for 10h; under 760.051 Torr; Schlenk technique; Inert atmosphere;

DOI:10.1021/jo5023102

Reference yield: 47.0%

N-pivaloylaniline (6625-74-7) + malonic acid dimethyl ester (108-59-8) → dimethyl 2-(2-(pivalamido)phenyl)malonate (1452922-60-9)

Guidance literature:

With palladium diacetate; manganese(III) triacetate dihydrate; trifluoroacetic acid; In toluene; Inert atmosphere; Schlenk technique;

DOI:10.1039/c3cc44769c

upstream raw materials:

N-pivaloylaniline

malonic acid dimethyl ester

dimethyl diazomalonate