(E)-1-phenylethan-1-one O-pivaloyl oxime

Base Information

• Chemical Name: (E)-1-phenylethan-1-one O-pivaloyl oxime
• CAS No.: 1293990-84-7
• Molecular Formula: C₁₃H₁₇NO₂
• Molecular Weight: 219.283
• Mol file: 1293990-84-7.mol

Synonyms:(E)-1-phenylethan-1-one O-pivaloyl oxime

Chemical Property of (E)-1-phenylethan-1-one O-pivaloyl oxime

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1-phenylethan-1-one O-pivaloyl oxime

There total 1 articles about (E)-1-phenylethan-1-one O-pivaloyl oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

acetophenone oxime (613-91-2) + 2,2-dimethylpropanoic anhydride (1538-75-6) → (E)-1-phenylethan-1-one O-pivaloyl oxime (1293990-84-7)

Guidance literature:

In dichloromethane; at 20 ℃; for 16h;

DOI:10.1021/ja201143v

Reference yield: 86.0%

(E)-1-phenylethan-1-one O-pivaloyl oxime (1293990-84-7) + diphenyl acetylene (501-65-5) → 1-methyl-3,4-diphenylisoquinoline (93472-50-5)

Guidance literature:

With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; potassium carbonate; In methanol; at 60 ℃; for 16h;

DOI:10.1021/ja201143v

Reference yield: 50.0%

Benzyl isocyanide (88333-03-3,10340-91-7) + (E)-1-phenylethan-1-one O-pivaloyl oxime (1293990-84-7) → 2,3,6-triphenyl-5H-pyrrolo[2,3-b]pyrazine (78605-18-2)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; 1,8-diazabicyclo[5.4.0]undec-7-ene; In toluene; for 24h; Reagent/catalyst; Solvent; Temperature; regioselective reaction; Catalytic behavior; Sealed tube; Reflux;

DOI:10.1002/adsc.201701202

upstream raw materials:

acetophenone oxime

2,2-dimethylpropanoic anhydride

Downstream raw materials:

1-methyl-3,4-diphenylisoquinoline

2,3,6-triphenyl-5H-pyrrolo[2,3-b]pyrazine

2-amino-4-(4-methyl-phenyl)-6-phenyl-pyridine-3-carbonitrile