(S)-3-Benzyl-4,4-dimethyl-2-oxo-hex-5-enoic acid isopropyl ester

Base Information

• Chemical Name: (S)-3-Benzyl-4,4-dimethyl-2-oxo-hex-5-enoic acid isopropyl ester
• CAS No.: 412967-24-9
• Molecular Formula: C₁₈H₂₄O₃
• Molecular Weight: 288.387
• Mol file: 412967-24-9.mol

Synonyms:(S)-3-Benzyl-4,4-dimethyl-2-oxo-hex-5-enoic acid isopropyl ester

Chemical Property of (S)-3-Benzyl-4,4-dimethyl-2-oxo-hex-5-enoic acid isopropyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (S)-3-Benzyl-4,4-dimethyl-2-oxo-hex-5-enoic acid isopropyl ester

There total 2 articles about (S)-3-Benzyl-4,4-dimethyl-2-oxo-hex-5-enoic acid isopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-2-(3-Methylbut-2-enyloxy)-4-phenylbut-2-enoic acid isopropyl ester (273928-99-7) → (S)-3-Benzyl-4,4-dimethyl-2-oxo-hex-5-enoic acid isopropyl ester (412967-24-9) + (R)-3-Benzyl-4,4-dimethyl-2-oxo-hex-5-enoic acid isopropyl ester

Guidance literature:

[Cu{(S,S)-t-Bu-bis(oxazoline)}](OTf)2; In dichloromethane; at 20 ℃; for 72h; Title compound not separated from byproducts.;

DOI:10.1016/j.tetlet.2004.03.047

Reference yield:

(Z)-2-(3-Methyl-but-2-enyloxy)-4-phenyl-but-2-enoic acid isopropyl ester → 2-oxo-4-phenyl-butyric acid isopropyl ester (83402-89-5) + 3-benzyl-6-methyl-2-oxo-hept-5-enoic acid isopropyl ester + (S)-3-Benzyl-4,4-dimethyl-2-oxo-hex-5-enoic acid isopropyl ester (412967-24-9) + (R)-3-Benzyl-4,4-dimethyl-2-oxo-hex-5-enoic acid isopropyl ester

Guidance literature:

[Cu((S,S)-((CH₃)3CCHCH₂OCN)2C(CH₃)2)(H₂O)2](SbF₆)2; In dichloromethane; at 20 ℃; for 24h; Further Variations:; Catalysts; reaction times; Product distribution;

DOI:10.1002/1521-3773(20011217)40:24<4700::AID-ANIE4700>3.0.CO;2-6

Reference yield:

(S)-3-Benzyl-4,4-dimethyl-2-oxo-hex-5-enoic acid isopropyl ester (412967-24-9) → (S)-3-Benzyl-4,4-dimethyl-hex-5-ene-1,2-diol

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1002/1521-3773(20011217)40:24<4700::AID-ANIE4700>3.0.CO;2-6

upstream raw materials:

(Z)-2-(3-Methylbut-2-enyloxy)-4-phenylbut-2-enoic acid isopropyl ester