C₁₁H₁₆O₂

Base Information

• Chemical Name: C₁₁H₁₆O₂
• CAS No.: 1380086-03-2
• Molecular Formula: C₁₁H₁₆O₂
• Molecular Weight: 180.247
• Mol file: 1380086-03-2.mol

Synonyms:C₁₁H₁₆O₂

Chemical Property of C₁₁H₁₆O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₁H₁₆O₂

There total 2 articles about C₁₁H₁₆O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

C19H24O3 → C11H16O2 (1380086-03-2)

Guidance literature:

With ammonium cerium (IV) nitrate; In water; acetonitrile; at 20 ℃; for 0.833333h; Reagent/catalyst; Solvent; Temperature; chemoselective reaction;

DOI:10.1021/acs.orglett.9b02144

Reference yield:

4-Methylbenzyl bromide (104-81-4) → C11H16O2 (1380086-03-2)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C

2: ammonium cerium (IV) nitrate / acetonitrile; water / 0.83 h / 20 °C

With ammonium cerium (IV) nitrate; potassium carbonate; In water; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1021/acs.orglett.9b02144

Reference yield: 88.0%

C11H16O2 (1380086-03-2) + benzylamine (100-46-9) → N-benzylpropanamide (10264-12-7) + N-benzyl-4-methylbenzamide (5436-83-9)

Guidance literature:

With dichloro(benzene)ruthenium(II) dimer; N,N-diisopropylimidazolium bromide; sodium hydride; In toluene; acetonitrile; for 24h; Inert atmosphere; Reflux;

DOI:10.1021/ol3009842

upstream raw materials:

4-Methylbenzyl bromide

Downstream raw materials:

N-benzylpropanamide

N-benzyl-4-methylbenzamide