10264-12-7Relevant articles and documents
Copper and N-Heterocyclic Carbene-Catalyzed Oxidative Amidation of Aldehydes with Amines
Singh, Ashmita,Narula, Anudeep Kumar
, p. 718 - 722 (2021)
A one-pot two-step oxidative process has been developed for the tert-butyl hydroperoxide mediated transformation of aldehydes and amines into amides catalyzed by copper(I) iodide and an N-heterocyclic carbene. The process is additive-free and does not require the amine to be transformed into its hydrochloride salts. The method is simple and practicable, has a broad substrate scope, and uses economical, feasible, and abundant reagents.
Cobalt(II)-Catalyzed N-Acylation of Amines through a Transamidation Reaction
Ma, Juan,Zhang, Feng,Zhang, Jingyu,Gong, Hang
, p. 4940 - 4948 (2018)
A practical protocol has been developed for a Co(OAc)2·4H2O-catalyzed transamidation reaction. The reaction gives high yields and uses N,N-dimethylformamide and other amides as carbonyl sources. The protocol is rapid and simple, and it does not require any acids, bases, ligands, or other additives. It works well for a wide range of primary, secondary, and heterocyclic amines.
On the reaction of acyl chlorides and carboxylic anhydrides with phosphazenes
Bosch, Imma,Gonzalez, Angel,Urpi, Felix,Vilarrasa, Jaume
, p. 5638 - 5643 (1996)
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First Carbamates Conversion to Amides by Simple Alkyl Group Transfer from Trialkylalanes
El Kaim, Laurent,Grimaud, Laurence,Lee, Anabelle,Perroux, Yannick,Tirla, Cornelia
, p. 381 - 383 (2004)
(Equation presented) N-Monosubstituted carbamates are cleanly converted to amides under treatment with trialkylaluminum. This reaction involves an aluminum-assisted internal delivery of alkyl groups. It can be applied to new and mild protecting group strategies for alcohols.
Hydrogen processing by FeIII-exchanged montmorillonite: A unique geochemical protocol
Choudary, Boyapati M.,Kantam, Mannepalli L.,Ranganath, Kalluri V. S.,Rao, Kottapalli K.
, p. 322 - 325 (2005)
The production of hydrogen by the relay of electrons from 1- to H+ in an acidic, aqueous medium and the consumption of hydrogen by reductive N acylation open up enormous opportunities in hydrogen chemistry (see scheme).
Transamidation catalyzed by a recoverable and reusable polyDMAP-based hafnium chloride and montmorillonite KSF
Shi, Min,Cui, Shi-Cong
, p. 2847 - 2858 (2005)
In this article, we described the use of an easily available polymer-based hafnium chloride and montmorillonite KSF catalyst (HfCl4/KSF- polyDMAP) in transamidation under relatively mild conditions. This metal catalyst can be easily recovered and reused in this reaction to give the corresponding amides in good yields. Copyright Taylor & Francis, Inc.
Oxidative activation of dihydropyridine amides to reactive acyl donors
Funder, Erik Daa,Trads, Julie B.,Gothelf, Kurt V.
, p. 185 - 198 (2015)
Amides of 1,4-dihydropyridine (DHP) are activated by oxidation for acyl transfer to amines, alcohols and thiols. In the reduced form the DHP amide is stable towards reaction with amines at room temperature. However, upon oxidation with DDQ the acyl donor is activated via a proposed pyridinium intermediate. The activated intermediate reacts with various nucleophiles to give amides, esters, and thio-esters in moderate to high yields. This journal is
N -Alkylation of organonitrogen compounds catalyzed by methylene-linked bis-NHC half-sandwich ruthenium complexes
Botubol-Ares, José Manuel,Collado, Isidro G.,Jiménez-Tenorio, Manuel,Moutaoukil, Zakaria,Serrano-Díez, Emmanuel
supporting information, p. 831 - 839 (2022/02/03)
An efficient ruthenium-catalyzed N-alkylation of amines, amides and sulfonamides has been developed employing novel pentamethylcyclopentadienylruthenium(ii) complexes bearing the methylene linked bis(NHC) ligand bis(3-methylimidazol-2-ylidene)methane. The
Mn(II)-Catalyzed N -Acylation of Amines
Ma, Juan,Zhang, Jingyu,Gong, Hang
, p. 693 - 703 (2019/01/23)
A practical protocol has been developed here for the Mn(II)-catalyzed N -acylation of amines with high yields using N, N -dimethylformamide and other amides as the carbonyl source. The protocol is simple, does not require any acid, base, ligand, or other additives, and encompasses a broad substrate scope for primary, secondary, and heterocyclic amines.
