1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one

Base Information

Chemical Name:1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one
CAS No.:18956-16-6
Molecular Formula:C₁₆H₁₄O₄
Molecular Weight:270.285
Hs Code.:
DSSTox Substance ID:DTXSID601298351
Wikidata:Q27216216
Mol file:18956-16-6.mol

Synonyms:1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one;1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one;Cardamomin;Alpinetin chalcone;(E)-Cardamomin;(E)-Alpinetin chalcone;DTXSID601298351;HMS3885E14;s3942;AKOS030241171;CCG-267160;(E)-2',4'-Dihydroxy-6'-methoxy-chalcone;FT-0697897;FT-0697915;Q27216216

Suppliers and Price of 1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one
20mg
$ 185.00

Oakwood
(E)-1-(2,4-Dihydroxy-6-methoxy-phenyl)-3-phenyl-propenone
20mg
$ 130.00

Oakwood
(E)-1-(2,4-Dihydroxy-6-methoxy-phenyl)-3-phenyl-propenone
50mg
$ 263.00

CSNpharm
Chalcone,2′,4′-dihydroxy-6′-methoxy-
50mg
$ 320.00

CSNpharm
Chalcone,2′,4′-dihydroxy-6′-methoxy-
5mg
$ 60.00

CSNpharm
Chalcone,2′,4′-dihydroxy-6′-methoxy-
10mg
$ 100.00

ChemScene
Cardamonin 98.54%
5mg
$ 68.00

ChemScene
Cardamonin 98.54%
10mg
$ 116.00

ChemScene
Cardamonin 98.54%
50mg
$ 350.00

American Custom Chemicals Corporation
CARDAMONIN 95.00%
20MG
$ 635.25

Total 24 raw suppliers

Chemical Property of 1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one

Chemical Property:

Vapor Pressure:5.2E-10mmHg at 25°C
Melting Point:178 °C
Boiling Point:484.5oC at 760 mmHg
PKA:7.00±0.40(Predicted)
Flash Point:182.7oC
PSA：66.76000
Density:1.282g/cm3
LogP:3.00250
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:270.08920892
Heavy Atom Count:20
Complexity:346

Purity/Quality:

99%, ^*data from raw suppliers

1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1C(=O)C=CC2=CC=CC=C2)O)O
Uses 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one is inhibits NO and PGE2 production and inhibits TXB2 production.

Technology Process of 1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one

There total 4 articles about 1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 84457-60-3
2'-hydroxy-4'-benzyloxy-6'methoxychalkone

: 19309-14-9,18956-16-6
2′,4′-dihydroxy-6′-methoxychalcone

Guidance literature:: With hydrogenchloride; acetic acid; at 50 - 60 ℃; for 0.5h;

Reference yield:

: 39548-89-5
1-(4-(benzyloxy)-2-hydroxy-6-methoxyphenyl)ethan-1-one

: 19309-14-9,18956-16-6
2′,4′-dihydroxy-6′-methoxychalcone

Guidance literature:: Multi-step reaction with 2 steps

1: 0.9 g / aq. KOH / ethanol / 72 h / Ambient temperature

2: 0.5 g / HCl, acetic acid / 0.5 h / 50 - 60 °C

With hydrogenchloride; potassium hydroxide; acetic acid; In ethanol;

Reference yield:

: 100-52-7
benzaldehyde

: 19309-14-9,18956-16-6
2′,4′-dihydroxy-6′-methoxychalcone

Guidance literature:: Multi-step reaction with 2 steps

1: 0.9 g / aq. KOH / ethanol / 72 h / Ambient temperature

2: 0.5 g / HCl, acetic acid / 0.5 h / 50 - 60 °C

With hydrogenchloride; potassium hydroxide; acetic acid; In ethanol;