(2R,3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)amino-2-hydroxydecanoate

Base Information

Chemical Name:(2R,3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)amino-2-hydroxydecanoate
CAS No.:157824-01-6
Molecular Formula:C₂₉H₄₃NO₃
Molecular Weight:453.665
Hs Code.:

Synonyms:(2R,3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)amino-2-hydroxydecanoate

Suppliers and Price of (2R,3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)amino-2-hydroxydecanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)amino-2-hydroxydecanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)amino-2-hydroxydecanoate

There total 4 articles about (2R,3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)amino-2-hydroxydecanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 38235-77-7
(R)-N-benzyl-1-phenylethylamine

: 87947-76-0
trans-2-decenoic acid tert-butyl ester

: 157824-01-6
(2R,3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)amino-2-hydroxydecanoate

Guidance literature:: (R)-N-benzyl-1-phenylethylamine; trans-2-decenoic acid tert-butyl ester; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 2h;

With (1R)-(-)-(10-camphorsulfonyl)oxaziridine; In tetrahydrofuran; at -78 - 20 ℃; for 12h;
DOI:10.1016/S0957-4166(02)00406-8

Reference yield:

: 87947-76-0
trans-2-decenoic acid tert-butyl ester

: lithium benzyl-(R)-1-phenylethylamide

: 157824-01-6
(2R,3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)amino-2-hydroxydecanoate

: (2S,3S)-3-[Benzyl-((R)-1-phenyl-ethyl)-amino]-2-hydroxy-decanoic acid tert-butyl ester

Guidance literature:: With (+)-(camphorsulfonyl)oxazoridinone; Yield given. Multistep reaction;
DOI:10.1016/S0957-4166(00)86173-X

Reference yield:

: 162285-06-5
(3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)aminodecanoate

: 157824-01-6
(2R,3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)amino-2-hydroxydecanoate

: (2S,3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)amino-2-hydroxydecanoate

Guidance literature:: With (+)-(2S,8aS)-(camphorylsulfonyl)oxaziridine; lithium diisopropyl amide; Yield given. Multistep reaction. Yields of byproduct given; 1.) THF, hexane, -78 deg C, 30 min, 2.) THF, hexane, -78 deg C, 1.5 h;
DOI:10.1016/0957-4166(94)00372-I