[1-(4-fluoro-phenyl)-2-oxo-pyrrolidin-3-yl]-phosphonic acid diethyl ester

Base Information

Chemical Name:[1-(4-fluoro-phenyl)-2-oxo-pyrrolidin-3-yl]-phosphonic acid diethyl ester
CAS No.:1062574-82-6
Molecular Formula:C₁₄H₁₉FNO₄P
Molecular Weight:315.281
Hs Code.:

Synonyms:[1-(4-fluoro-phenyl)-2-oxo-pyrrolidin-3-yl]-phosphonic acid diethyl ester

Suppliers and Price of [1-(4-fluoro-phenyl)-2-oxo-pyrrolidin-3-yl]-phosphonic acid diethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [1-(4-fluoro-phenyl)-2-oxo-pyrrolidin-3-yl]-phosphonic acid diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [1-(4-fluoro-phenyl)-2-oxo-pyrrolidin-3-yl]-phosphonic acid diethyl ester

There total 1 articles about [1-(4-fluoro-phenyl)-2-oxo-pyrrolidin-3-yl]-phosphonic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 54660-08-1
1-(4-fluoro-phenyl)-pyrrolidin-2-one

: 814-49-3
diethyl chlorophosphate

: 1062574-82-6
[1-(4-fluoro-phenyl)-2-oxo-pyrrolidin-3-yl]-phosphonic acid diethyl ester

Guidance literature:: 1-(4-fluoro-phenyl)-pyrrolidin-2-one; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at 20 ℃; Inert atmosphere;

diethyl chlorophosphate; In tetrahydrofuran; hexane; at 20 ℃; Inert atmosphere;
DOI:10.1021/ol8017209

Reference yield: 14.0%

: 626-96-0
4-oxopentanal

: 1062574-82-6
[1-(4-fluoro-phenyl)-2-oxo-pyrrolidin-3-yl]-phosphonic acid diethyl ester

: 1062575-47-6
(Z)-1-(4-fluorophenyl)-3-[4-oxo-pentylidene]-pyrrolidin-2-one

: 1062575-46-5
(E)-1-(4-fluorophenyl)-3-[4-oxo-pentylidene]-pyrrolidin-2-one

Guidance literature:: [1-(4-fluoro-phenyl)-2-oxo-pyrrolidin-3-yl]-phosphonic acid diethyl ester; With 18-crown-6 ether; potassium hexamethylsilazane; In tetrahydrofuran; toluene; at -78 ℃; for 0.5h; Inert atmosphere;

4-oxopentanal; In tetrahydrofuran; toluene; at -78 - 20 ℃; Inert atmosphere;
DOI:10.1021/ol8017209