C₃₂H₂₉N₃O₂

Base Information

• Chemical Name: C₃₂H₂₉N₃O₂
• CAS No.: 1337570-08-7
• Molecular Formula: C₃₂H₂₉N₃O₂
• Molecular Weight: 487.601
• Mol file: 1337570-08-7.mol

Synonyms:C₃₂H₂₉N₃O₂

Chemical Property of C₃₂H₂₉N₃O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₂H₂₉N₃O₂

There total 5 articles about C₃₂H₂₉N₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

C18H15BrN2 (1360866-28-9) + bis(4-methoxyphenyl)amine (101-70-2) → C32H29N3O2 (1337570-08-7)

Guidance literature:

With tri-tert-butyl phosphine; potassium tert-butylate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In toluene; at 80 ℃; for 48h; Inert atmosphere;

DOI:10.1039/c1cc13831f

Reference yield:

2,5-dimethyl-4-trimethylsilyl-1-phenylboronic acid (1059575-28-8) → C32H29N3O2 (1337570-08-7)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / ethanol; water; toluene / Inert atmosphere; Reflux

2: bromine; sodium acetate / tetrahydrofuran / 2 h / 20 °C / Cooling with ice; Darkness

3: tri-tert-butyl phosphine; potassium tert-butylate; bis(dibenzylideneacetone)-palladium⁽⁰⁾ / toluene / 48 h / 80 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; tri-tert-butyl phosphine; potassium tert-butylate; bromine; sodium acetate; sodium carbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; ethanol; water; toluene; 1: Suzuki coupling;

DOI:10.1039/c1cc13831f

Reference yield:

bpy-xy-TMS (1337570-07-6) → C32H29N3O2 (1337570-08-7)

Guidance literature:

Multi-step reaction with 2 steps

1: bromine; sodium acetate / tetrahydrofuran / 2 h / 20 °C / Cooling with ice; Darkness

2: tri-tert-butyl phosphine; potassium tert-butylate; bis(dibenzylideneacetone)-palladium⁽⁰⁾ / toluene / 48 h / 80 °C / Inert atmosphere

With tri-tert-butyl phosphine; potassium tert-butylate; bromine; sodium acetate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; toluene;

DOI:10.1039/c1cc13831f

upstream raw materials:

2,5-dimethyl-4-trimethylsilyl-1-phenylboronic acid

bpy-xy-TMS

C₁₈H₁₅BrN₂

bis(4-methoxyphenyl)amine