methyl (2R)-2-[N-(t-butoxycarbonyl)amino]-3-(4-phenoxy)thiophenoxypropionate

Base Information

Chemical Name:methyl (2R)-2-[N-(t-butoxycarbonyl)amino]-3-(4-phenoxy)thiophenoxypropionate
CAS No.:1009373-07-2
Molecular Formula:C₂₁H₂₅NO₅S
Molecular Weight:403.499
Hs Code.:

Synonyms:methyl (2R)-2-[N-(t-butoxycarbonyl)amino]-3-(4-phenoxy)thiophenoxypropionate

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Chemical Property of methyl (2R)-2-[N-(t-butoxycarbonyl)amino]-3-(4-phenoxy)thiophenoxypropionate

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Technology Process of methyl (2R)-2-[N-(t-butoxycarbonyl)amino]-3-(4-phenoxy)thiophenoxypropionate

There total 1 articles about methyl (2R)-2-[N-(t-butoxycarbonyl)amino]-3-(4-phenoxy)thiophenoxypropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 38778-05-1
4-(Phenoxy)benzenethiol

: 56926-94-4
methyl (2S)-2-[N-(t-butoxycarbonyl)amino]-3-(4-methylbenzenesulfonyl)-oxypropionate

: 1009373-07-2
methyl (2R)-2-[N-(t-butoxycarbonyl)amino]-3-(4-phenoxy)thiophenoxypropionate

Guidance literature:: 4-(Phenoxy)benzenethiol; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.0833333h;

methyl (2S)-2-[N-(t-butoxycarbonyl)amino]-3-(4-methylbenzenesulfonyl)-oxypropionate; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

Reference yield: 96.0%

: 1009373-07-2
methyl (2R)-2-[N-(t-butoxycarbonyl)amino]-3-(4-phenoxy)thiophenoxypropionate

: 1009373-08-3
(2R)-2-[N-(t-butoxycarbonyl)amino]-3-(4-phenoxy)thiophenoxypropionic acid

Guidance literature:: methyl (2R)-2-[N-(t-butoxycarbonyl)amino]-3-(4-phenoxy)thiophenoxypropionate; With lithium hydroxide; water; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; water; ethyl acetate;