Technology Process of N-methyl-3-iodo-4-(p-methoxyphenyl)-1-azaspiro[4,5]deca-3,6,9-triene-2,8-dione
There total 5 articles about N-methyl-3-iodo-4-(p-methoxyphenyl)-1-azaspiro[4,5]deca-3,6,9-triene-2,8-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium perchlorate; lithium iodide;
In
acetonitrile;
at 20 ℃;
for 2h;
Electrochemical reaction;
DOI:10.1021/acs.joc.0c02429
- Guidance literature:
-
Multi-step reaction with 2 steps
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / tetrahydrofuran / 70 °C / Inert atmosphere
2: bis-[(trifluoroacetoxy)iodo]benzene; sodium acetate; oxygen / acetonitrile / 18 h / 20 °C / Schlenk technique; Irradiation; Green chemistry
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; oxygen; sodium acetate; triethylamine; bis-[(trifluoroacetoxy)iodo]benzene;
In
tetrahydrofuran; acetonitrile;
DOI:10.1039/d0ob00057d
- Guidance literature:
-
Multi-step reaction with 3 steps
1: dicyclohexyl-carbodiimide / dichloromethane / 0 - 20 °C
2: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / tetrahydrofuran / 70 °C / Inert atmosphere
3: bis-[(trifluoroacetoxy)iodo]benzene; sodium acetate; oxygen / acetonitrile / 18 h / 20 °C / Schlenk technique; Irradiation; Green chemistry
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; oxygen; sodium acetate; triethylamine; dicyclohexyl-carbodiimide; bis-[(trifluoroacetoxy)iodo]benzene;
In
tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1039/d0ob00057d
