(R,2E,6E)-1-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-3,7,8-trimethyl-5-phenylsulfonyldeca-2,6-diene

Base Information

Chemical Name:(R,2E,6E)-1-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-3,7,8-trimethyl-5-phenylsulfonyldeca-2,6-diene
CAS No.:270258-33-8
Molecular Formula:C₄₁H₆₀O₄SSi₂
Molecular Weight:705.162
Hs Code.:

Synonyms:(R,2E,6E)-1-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-3,7,8-trimethyl-5-phenylsulfonyldeca-2,6-diene

Suppliers and Price of (R,2E,6E)-1-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-3,7,8-trimethyl-5-phenylsulfonyldeca-2,6-diene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R,2E,6E)-1-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-3,7,8-trimethyl-5-phenylsulfonyldeca-2,6-diene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R,2E,6E)-1-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-3,7,8-trimethyl-5-phenylsulfonyldeca-2,6-diene

There total 14 articles about (R,2E,6E)-1-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-3,7,8-trimethyl-5-phenylsulfonyldeca-2,6-diene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 108734-49-2
(E)-4-(tert-butyldimethylsilyloxy)-1-chloro-2-methyl-2-butene

: 270258-32-7
(R,E)-6-(tert-butyldiphenylsilyloxy)-3,4-dimethyl-1-phenylsulfonyl-2-hexene

: 270258-33-8
(R,2E,6E)-1-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-3,7,8-trimethyl-5-phenylsulfonyldeca-2,6-diene

Guidance literature:: (R,E)-6-(tert-butyldiphenylsilyloxy)-3,4-dimethyl-1-phenylsulfonyl-2-hexene; With n-butyllithium; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; at -50 ℃; for 0.5h;

(E)-4-(tert-butyldimethylsilyloxy)-1-chloro-2-methyl-2-butene; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; at 4 ℃; for 18h; Further stages.;
DOI:10.1002/(sici)1099-0690(200003)2000:6<955::aid-ejoc955>3.0.co;2-y

Reference yield: 78.0%

: 270258-26-9
(E)-tert-butyl(4-chloro-2-methylbut-2-en-1-yloxy)dimethylsilane

: 270258-32-7
(R,E)-6-(tert-butyldiphenylsilyloxy)-3,4-dimethyl-1-phenylsulfonyl-2-hexene

: 270258-33-8
(R,2E,6E)-1-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-3,7,8-trimethyl-5-phenylsulfonyldeca-2,6-diene

Guidance literature:: (R,E)-6-(tert-butyldiphenylsilyloxy)-3,4-dimethyl-1-phenylsulfonyl-2-hexene; With n-butyllithium; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide;

(E)-tert-butyl(4-chloro-2-methylbut-2-en-1-yloxy)dimethylsilane; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide;
DOI:10.1039/a907910f

Reference yield:

: 270258-30-5
(R,E)-6-(tert-butyldiphenylsilyloxy)-3,4-dimethyl-2-hexen-1-ol

: 270258-33-8
(R,2E,6E)-1-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-3,7,8-trimethyl-5-phenylsulfonyldeca-2,6-diene

Guidance literature:: Multi-step reaction with 3 steps

1.1: CCl₄; PPh₃ / 6 h / Heating

2.1: dimethylformamide / 15 h / 20 °C

3.1: n-BuLi / tetrahydrofuran; hexamethylphosphoric acid triamide; hexane / 0.5 h / -50 °C

3.2: 88 percent / tetrahydrofuran; hexamethylphosphoric acid triamide; hexane / 18 h / 4 °C

With tetrachloromethane; n-butyllithium; triphenylphosphine; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; N,N-dimethyl-formamide; 1.1: Chlorination / 2.1: Substitution / 3.1: Metallation / 3.2: Alkylation;
DOI:10.1002/(sici)1099-0690(200003)2000:6<955::aid-ejoc955>3.0.co;2-y