2,6-diethyl-4-methylphenyl boronic acid

Base Information

• Chemical Name: 2,6-diethyl-4-methylphenyl boronic acid
• CAS No.: 953075-90-6
• Molecular Formula: C₁₁H₁₇BO₂
• Molecular Weight: 192.066
• Mol file: 953075-90-6.mol

Synonyms:2,6-diethyl-4-methylphenyl boronic acid

Chemical Property of 2,6-diethyl-4-methylphenyl boronic acid

Chemical Property:

• Boiling Point: 337.2±52.0 °C(Predicted)
• Density: 1.02±0.1 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

(2,6-Diethyl-4-methylphenyl)boronicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-diethyl-4-methylphenyl boronic acid

There total 3 articles about 2,6-diethyl-4-methylphenyl boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.2%

Trimethyl borate (121-43-7,63156-11-6) + 1-bromo-2,6-diethyl-4-methylbenzene (314084-61-2) → 2,6-diethyl-4-methylphenyl boronic acid (953075-90-6)

Guidance literature:

1-bromo-2,6-diethyl-4-methylbenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -65 ℃; for 0.5h; Inert atmosphere;

Trimethyl borate; In tetrahydrofuran; hexane; at -65 ℃; for 0.5h; Inert atmosphere;

Reference yield: 78.0%

1-bromo-2,6-diethyl-4-methylbenzene (314084-61-2) → 2,6-diethyl-4-methylphenyl boronic acid (953075-90-6)

Guidance literature:

1-bromo-2,6-diethyl-4-methylbenzene; With n-butyllithium; In tetrahydrofuran; hexanes; at -78 ℃; for 0.333333h;

With Trimethyl borate; In tetrahydrofuran; hexanes; at -78 ℃; for 0.5h;

With hydrogenchloride; water; In tetrahydrofuran; hexanes;

Reference yield:

→ 2,6-diethyl-4-methylphenyl boronic acid (953075-90-6)

Guidance literature:

upstream raw materials:

Trimethyl borate

1-bromo-2,6-diethyl-4-methylbenzene

Downstream raw materials:

2-(2,6-diethyl-4-methylphenyl)-3-methoxy-cyclopent-2-en-1-one

2-(2,6-diethyl-4-methylphenyl)-5-([1,3]dioxolan-2-ylmethyl)cyclohexane-1,3-dione

(2,6-diethyl-4-methylphenyl)acetic acid ethyl ester

C₂₅H₂₅F₅O₂S