Technology Process of (2S)-2-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-3-phenyl-1-propanol
There total 4 articles about (2S)-2-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-3-phenyl-1-propanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: lithium hexamethyldisilazane; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran
2: lithium aluminium tetrahydride / tetrahydrofuran
3: toluene-4-sulfonic acid
With
N,N,N,N,N,N-hexamethylphosphoric triamide; lithium aluminium tetrahydride; toluene-4-sulfonic acid; lithium hexamethyldisilazane;
In
tetrahydrofuran;
DOI:10.1016/j.bmcl.2014.04.054
- Guidance literature:
-
Multi-step reaction with 2 steps
1: lithium aluminium tetrahydride / tetrahydrofuran
2: toluene-4-sulfonic acid
With
lithium aluminium tetrahydride; toluene-4-sulfonic acid;
In
tetrahydrofuran;
DOI:10.1016/j.bmcl.2014.04.054
- Guidance literature:
-
benzyl bromide; dibenzyl (2S)-2-hydroxybutanedioate;
With
N,N,N,N,N,N-hexamethylphosphoric triamide; lithium hexamethyldisilazane;
In
tetrahydrofuran;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
With
toluene-4-sulfonic acid;
In
acetone;
DOI:10.1016/j.bmcl.2014.04.054
