methyl 3α-(3-dimethoxyformylbenzoyloxy)-12α-pyridine-3-carboxy-5β-deoxycholan-24-oate

Base Information

• Chemical Name: methyl 3α-(3-dimethoxyformylbenzoyloxy)-12α-pyridine-3-carboxy-5β-deoxycholan-24-oate
• CAS No.: 1221177-38-3
• Molecular Formula: C₄₁H₅₅NO₈
• Molecular Weight: 689.89
• Mol file: 1221177-38-3.mol

Synonyms:methyl 3α-(3-dimethoxyformylbenzoyloxy)-12α-pyridine-3-carboxy-5β-deoxycholan-24-oate

Chemical Property of methyl 3α-(3-dimethoxyformylbenzoyloxy)-12α-pyridine-3-carboxy-5β-deoxycholan-24-oate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of methyl 3α-(3-dimethoxyformylbenzoyloxy)-12α-pyridine-3-carboxy-5β-deoxycholan-24-oate

There total 1 articles about methyl 3α-(3-dimethoxyformylbenzoyloxy)-12α-pyridine-3-carboxy-5β-deoxycholan-24-oate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

nicotinic acid (59-67-6) + methyl 3α-(3-dimethoxyformylbenzoyloxy)-12α-hydroxy-5β-deoxycholan-24-oate (1221177-18-9) → methyl 3α-(3-dimethoxyformylbenzoyloxy)-12α-pyridine-3-carboxy-5β-deoxycholan-24-oate (1221177-38-3)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃;

DOI:10.1039/b917145b

Reference yield: 69.5%

methyl 3α-(3-dimethoxyformylbenzoyloxy)-12α-pyridine-3-carboxy-5β-deoxycholan-24-oate (1221177-38-3) → 3α-(3-dimethoxyformylbenzoyloxy)-12-α-pyridine-3-carboxy-5β-deoxycholan-24-oic hydrazide (1221177-20-3)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; methanol; at 20 ℃; for 48h;

DOI:10.1039/b917145b

upstream raw materials:

nicotinic acid

methyl 3α-(3-dimethoxyformylbenzoyloxy)-12α-hydroxy-5β-deoxycholan-24-oate

Downstream raw materials:

3α-(3-dimethoxyformylbenzoyloxy)-12-α-pyridine-3-carboxy-5β-deoxycholan-24-oic hydrazide