(E,E)-2,3-bis-(4-methoxy-α-phenylethylidene)succinic anhydride

Base Information

• Chemical Name: (E,E)-2,3-bis-(4-methoxy-α-phenylethylidene)succinic anhydride
• CAS No.: 1333238-01-9
• Molecular Formula: C₂₂H₂₀O₅
• Molecular Weight: 364.398
• Mol file: 1333238-01-9.mol

Synonyms:(E,E)-2,3-bis-(4-methoxy-α-phenylethylidene)succinic anhydride

Chemical Property of (E,E)-2,3-bis-(4-methoxy-α-phenylethylidene)succinic anhydride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E,E)-2,3-bis-(4-methoxy-α-phenylethylidene)succinic anhydride

There total 6 articles about (E,E)-2,3-bis-(4-methoxy-α-phenylethylidene)succinic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C22H22O6 → (E,E)-2,3-bis-(4-methoxy-α-phenylethylidene)succinic anhydride (1333238-01-9)

Guidance literature:

With acetyl chloride; for 8h; Reflux;

DOI:10.1016/j.tetasy.2011.06.007

Reference yield:

diethyl (E,E)-2,3-bis-(4-methoxy-α-phenylethylidene)succinate (1333238-00-8) → (E,E)-2,3-bis-(4-methoxy-α-phenylethylidene)succinic anhydride (1333238-01-9)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium hydroxide / ethanol / Reflux

2: acetyl chloride / 8 h / Reflux

With acetyl chloride; lithium hydroxide; In ethanol;

DOI:10.1016/j.tetasy.2011.06.007

Reference yield:

C24H26O6 → (E,E)-2,3-bis-(4-methoxy-α-phenylethylidene)succinic anhydride (1333238-01-9)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / dimethyl sulfoxide; acetone / 15 h / Reflux

2: lithium hydroxide / ethanol / Reflux

3: acetyl chloride / 8 h / Reflux

With potassium carbonate; acetyl chloride; lithium hydroxide; In ethanol; dimethyl sulfoxide; acetone;

DOI:10.1016/j.tetasy.2011.06.007

upstream raw materials:

diethyl (E,E)-2,3-bis-(4-methoxy-α-phenylethylidene)succinate

ethyl (α-(4-methoxy-phenyl)ethylidene)succinate

diethyl (4-methoxy-α-phenylethylidene)succinate

1-(4-methoxyphenyl)ethanone

Downstream raw materials:

C₂₇H₂₉NO₅