(2-(3-methylbuta-1,2-dienyl)-2-(oct-2-ynyl)propane-1,3-diyl)bis(oxy)bis(methylene)dibenzene

Base Information

• Chemical Name: (2-(3-methylbuta-1,2-dienyl)-2-(oct-2-ynyl)propane-1,3-diyl)bis(oxy)bis(methylene)dibenzene
• CAS No.: 1448223-13-9
• Molecular Formula: C₃₀H₃₈O₂
• Molecular Weight: 430.631
• Mol file: 1448223-13-9.mol

Synonyms:(2-(3-methylbuta-1,2-dienyl)-2-(oct-2-ynyl)propane-1,3-diyl)bis(oxy)bis(methylene)dibenzene

Chemical Property of (2-(3-methylbuta-1,2-dienyl)-2-(oct-2-ynyl)propane-1,3-diyl)bis(oxy)bis(methylene)dibenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-(3-methylbuta-1,2-dienyl)-2-(oct-2-ynyl)propane-1,3-diyl)bis(oxy)bis(methylene)dibenzene

There total 2 articles about (2-(3-methylbuta-1,2-dienyl)-2-(oct-2-ynyl)propane-1,3-diyl)bis(oxy)bis(methylene)dibenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-(3-methylbuta-1,2-dienyl)-2-(oct-2-ynyl)propane-1,3-diol + benzyl bromide (100-39-0) → (2-(3-methylbuta-1,2-dienyl)-2-(oct-2-ynyl)propane-1,3-diyl)bis(oxy)bis(methylene)dibenzene (1448223-13-9)

Guidance literature:

2-(3-methylbuta-1,2-dienyl)-2-(oct-2-ynyl)propane-1,3-diol; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 1h;

benzyl bromide; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃;

DOI:10.1002/anie.201208718

Reference yield:

dimethyl 2-(3-methylbuta-1,2-dienyl)-2-(oct-2-ynyl)malonate (1374685-95-6) → (2-(3-methylbuta-1,2-dienyl)-2-(oct-2-ynyl)propane-1,3-diyl)bis(oxy)bis(methylene)dibenzene (1448223-13-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: lithium aluminium tetrahydride / diethyl ether / 1.5 h / 20 °C

2.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 1 h / 0 °C

2.2: 0 - 20 °C

With lithium aluminium tetrahydride; sodium hydride; In diethyl ether; N,N-dimethyl-formamide; mineral oil;

DOI:10.1002/anie.201208718

Reference yield: 70.0%

(2-(3-methylbuta-1,2-dienyl)-2-(oct-2-ynyl)propane-1,3-diyl)bis(oxy)bis(methylene)dibenzene (1448223-13-9) + acetic acid (64-19-7,77671-22-8) → 2-(3,3-bis(benzyloxymethyl)-5-(hex-1-enylidene)cyclopent-1-enyl)propan-2-yl acetate

Guidance literature:

With palladium diacetate; p-benzoquinone; In [⁽²⁾H₆]acetone; at 60 ℃; for 17h;

DOI:10.1002/anie.201208718

upstream raw materials:

benzyl bromide

dimethyl 2-(3-methylbuta-1,2-dienyl)-2-(oct-2-ynyl)malonate

Downstream raw materials:

(E)-2-(1-(4,4-bis(benzyloxymethyl)-2-(prop-1-en-2-yl)cyclopent-2-enylidene)hexyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane