2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-D-GLUCOHYDROXIMO-1,5-LACTONE

Base Information

• Chemical Name: 2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-D-GLUCOHYDROXIMO-1,5-LACTONE
• CAS No.: 132152-78-4
• Molecular Formula: C14H20 N2 O9
• Molecular Weight: 360.32
• Hs Code.: 29322090
• Mol file: 132152-78-4.mol

Synonyms:2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucohydroximo-1,5-lactone;

Chemical Property of 2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-D-GLUCOHYDROXIMO-1,5-LACTONE

Chemical Property:

• PSA: 149.82000
• LogP: -0.50500

Purity/Quality:

98%Min ^*data from raw suppliers

2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucohydroximo-1,5-lactone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-D-GLUCOHYDROXIMO-1,5-LACTONE

There total 1 articles about 2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-D-GLUCOHYDROXIMO-1,5-LACTONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H22N2O10 (132152-77-3) → Acetic acid (2R,3S,4R,5R)-3-acetoxy-2-acetoxymethyl-5-acetylamino-6-[(Z)-hydroxyimino]-tetrahydro-pyran-4-yl ester (132152-78-4)

Guidance literature:

With methylamine; In methanol; Yield given;

DOI:10.1002/hlca.19900730714

Reference yield: 94.0%

Acetic acid (2R,3S,4R,5R)-3-acetoxy-2-acetoxymethyl-5-acetylamino-6-[(Z)-hydroxyimino]-tetrahydro-pyran-4-yl ester (132152-78-4) + phenyl isocyanate (103-71-9) → O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucopyranosylidene)amino N-phenylcarbamate (132063-04-8)

Guidance literature:

With triethylamine; In tetrahydrofuran; for 3h;

DOI:10.1002/hlca.19900730714

Reference yield:

Acetic acid (2R,3S,4R,5R)-3-acetoxy-2-acetoxymethyl-5-acetylamino-6-[(Z)-hydroxyimino]-tetrahydro-pyran-4-yl ester (132152-78-4) → O-(2-acetamido-2-deoxy-D-glucopyranosylidene) amino-N-phenylcarbamate (132489-69-1,132063-05-9,872611-16-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / Et₃N / tetrahydrofuran / 3 h

2: 61 percent / NH₃/MeOH / 4 h

With methanol; ammonia; triethylamine; In tetrahydrofuran;

DOI:10.1002/hlca.19900730714

upstream raw materials:

C₁₆H₂₂N₂O₁₀

Downstream raw materials:

O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucopyranosylidene)amino N-phenylcarbamate

O-(2-acetamido-2-deoxy-D-glucopyranosylidene) amino-N-phenylcarbamate