2-(2-(3-bromo-5-(4,5-dihydro-4,4-dimethyloxazol-2-yl)pyridin-2-yl)phenyl)-2-ethylbutan-1-ol

Base Information

• Chemical Name: 2-(2-(3-bromo-5-(4,5-dihydro-4,4-dimethyloxazol-2-yl)pyridin-2-yl)phenyl)-2-ethylbutan-1-ol
• CAS No.: 925453-02-7
• Molecular Formula: C₂₂H₂₇BrN₂O₂
• Molecular Weight: 431.373
• Mol file: 925453-02-7.mol

Synonyms:2-(2-(3-bromo-5-(4,5-dihydro-4,4-dimethyloxazol-2-yl)pyridin-2-yl)phenyl)-2-ethylbutan-1-ol

Chemical Property of 2-(2-(3-bromo-5-(4,5-dihydro-4,4-dimethyloxazol-2-yl)pyridin-2-yl)phenyl)-2-ethylbutan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-(2-(3-bromo-5-(4,5-dihydro-4,4-dimethyloxazol-2-yl)pyridin-2-yl)phenyl)-2-ethylbutan-1-ol

There total 1 articles about 2-(2-(3-bromo-5-(4,5-dihydro-4,4-dimethyloxazol-2-yl)pyridin-2-yl)phenyl)-2-ethylbutan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C22H29BrN2O2 → 2-(2-(3-bromo-5-(4,5-dihydro-4,4-dimethyloxazol-2-yl)pyridin-2-yl)phenyl)-2-ethylbutan-1-ol (925453-02-7)

Guidance literature:

With chloranil; In toluene; for 2h; Heating;

DOI:10.1039/b613173e

Reference yield: 67.0%

2-(2-(3-bromo-5-(4,5-dihydro-4,4-dimethyloxazol-2-yl)pyridin-2-yl)phenyl)-2-ethylbutan-1-ol (925453-02-7) + tert-butyldimethylsilyl chloride (18162-48-6) → 3-bromo-5-(4,5-dihydro-4,4-dimethyloxazol-2-yl)-2-(2-(3-(((1,1-dimethylethyl)dimethylsilyloxy)methyl)pentan-3-yl)phenyl)pyridine (925453-08-3)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 25 ℃; for 2h;

DOI:10.1039/b613173e

Reference yield:

2-(2-(3-bromo-5-(4,5-dihydro-4,4-dimethyloxazol-2-yl)pyridin-2-yl)phenyl)-2-ethylbutan-1-ol (925453-02-7) + Trichloroacetyl isocyanate (3019-71-4) → C24H26BrN3O4

Guidance literature:

In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1039/b613173e

Downstream raw materials:

3-bromo-5-(4,5-dihydro-4,4-dimethyloxazol-2-yl)-2-(2-(3-(((1,1-dimethylethyl)dimethylsilyloxy)methyl)pentan-3-yl)phenyl)pyridine