N^α-(benzyloxycarbonyl)-N^γ-(6-O-(3,4-di-O-acetyl-2-O-benzyl-α-L-fucopyranosyl)-3-O-benzyl-2-deoxy-4-O-(9-fluorenylmethoxycarbonyl)-2-(2,2,2-trichloroethyloxycarbonylamino)-β-D-glucopyranosyl)-L-asparagine allyl ester

Base Information

• Chemical Name: N^α-(benzyloxycarbonyl)-N^γ-(6-O-(3,4-di-O-acetyl-2-O-benzyl-α-L-fucopyranosyl)-3-O-benzyl-2-deoxy-4-O-(9-fluorenylmethoxycarbonyl)-2-(2,2,2-trichloroethyloxycarbonylamino)-β-D-glucopyranosyl)-L-asparagine allyl ester
• CAS No.: 1182846-85-0
• Molecular Formula: C₆₃H₆₆Cl₃N₃O₁₉
• Molecular Weight: 1275.58
• Mol file: 1182846-85-0.mol

Synonyms:N^α-(benzyloxycarbonyl)-N^γ-(6-O-(3,4-di-O-acetyl-2-O-benzyl-α-L-fucopyranosyl)-3-O-benzyl-2-deoxy-4-O-(9-fluorenylmethoxycarbonyl)-2-(2,2,2-trichloroethyloxycarbonylamino)-β-D-glucopyranosyl)-L-asparagine allyl ester

Chemical Property of N^α-(benzyloxycarbonyl)-N^γ-(6-O-(3,4-di-O-acetyl-2-O-benzyl-α-L-fucopyranosyl)-3-O-benzyl-2-deoxy-4-O-(9-fluorenylmethoxycarbonyl)-2-(2,2,2-trichloroethyloxycarbonylamino)-β-D-glucopyranosyl)-L-asparagine allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N^α-(benzyloxycarbonyl)-N^γ-(6-O-(3,4-di-O-acetyl-2-O-benzyl-α-L-fucopyranosyl)-3-O-benzyl-2-deoxy-4-O-(9-fluorenylmethoxycarbonyl)-2-(2,2,2-trichloroethyloxycarbonylamino)-β-D-glucopyranosyl)-L-asparagine allyl ester

There total 1 articles about N^α-(benzyloxycarbonyl)-N^γ-(6-O-(3,4-di-O-acetyl-2-O-benzyl-α-L-fucopyranosyl)-3-O-benzyl-2-deoxy-4-O-(9-fluorenylmethoxycarbonyl)-2-(2,2,2-trichloroethyloxycarbonylamino)-β-D-glucopyranosyl)-L-asparagine allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

6-O-(3,4-di-O-acetyl-2-O-benzyl-α-L-fucopyranosyl)-3-O-benzyl-2-deoxy-4-O-(9-fluorenylmethoxycarbonyl)-2-(2,2,2-trichloroethoxycarbonylamino)-D-glucopyranosyl N-phenyltrifluoroacetimidate (1182846-83-8) + (S)-2-((benzyloxycarbonyl)amino)succinic acid 1-allyl ester 4-amide (848047-83-6) → Nα-(benzyloxycarbonyl)-Nγ-(6-O-(3,4-di-O-acetyl-2-O-benzyl-α-L-fucopyranosyl)-3-O-benzyl-2-deoxy-4-O-(9-fluorenylmethoxycarbonyl)-2-(2,2,2-trichloroethyloxycarbonylamino)-β-D-glucopyranosyl)-L-asparagine allyl ester (1182846-85-0)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1055/s-0029-1217343

Reference yield: 90.0%

Nα-(benzyloxycarbonyl)-Nγ-(6-O-(3,4-di-O-acetyl-2-O-benzyl-α-L-fucopyranosyl)-3-O-benzyl-2-deoxy-4-O-(9-fluorenylmethoxycarbonyl)-2-(2,2,2-trichloroethyloxycarbonylamino)-β-D-glucopyranosyl)-L-asparagine allyl ester (1182846-85-0) → Nα-(benzyloxycarbonyl)-Nγ-(6-O-(3,4-di-O-acetyl-2-O-benzyl-α-L-fucopyranosyl)-3-O-benzyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl)-L-asparagine allyl ester

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1021/acs.joc.6b02106

upstream raw materials:

6-O-(3,4-di-O-acetyl-2-O-benzyl-α-L-fucopyranosyl)-3-O-benzyl-2-deoxy-4-O-(9-fluorenylmethoxycarbonyl)-2-(2,2,2-trichloroethoxycarbonylamino)-D-glucopyranosyl N-phenyltrifluoroacetimidate

(S)-2-((benzyloxycarbonyl)amino)succinic acid 1-allyl ester 4-amide