848047-83-6

Basic information

• Product Name: (S)-2-((benzyloxycarbonyl)amino)succinic acid 1-allyl ester 4-amide
• Synonyms: (S)-2-((benzyloxycarbonyl)amino)succinic acid 1-allyl ester 4-amide
• CAS NO: 848047-83-6
• Molecular Weight: 306.318
• Mol File: 848047-83-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-2-((benzyloxycarbonyl)amino)succinic acid 1-allyl ester 4-amide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((benzyloxycarbonyl)amino)succinic acid 1-allyl ester 4-amide(848047-83-6)
• EPA Substance Registry System: (S)-2-((benzyloxycarbonyl)amino)succinic acid 1-allyl ester 4-amide(848047-83-6)

Safety Data

• Hazardous Substances Data: 848047-83-6(Hazardous Substances Data)

Upstream product

• 2304-96-3 N-benzyloxycarbonyl-L-asparagine 
• 106-95-6 allyl bromide 

Downstream Products

• 99701-64-1 N-((2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)-methyl)-tetrahydro-2H-pyran-2-yl)-2,2,2-trichloroacetamide 
• 1200438-00-1 (2S,6S)-4-oxo-2-phenyltetrahydropyrimidine-1,6(2H)-dicarboxylic acid 6-allyl ester 1-benzyl ester 
• 1200437-96-2 (2R,6S)-4-oxo-2-phenyltetrahydropyrimidine-1,6(2H)-dicarboxylic acid 6-allyl ester 1-benzyl ester 
• 1182846-85-0 N^α-(benzyloxycarbonyl)-N^γ-(6-O-(3,4-di-O-acetyl-2-O-benzyl-α-L-fucopyranosyl)-3-O-benzyl-2-deoxy-4-O-(9-fluorenylmethoxycarbonyl)-2-(2,2,2-trichloroethyloxycarbonylamino)-β-D-glucopyranosyl)-L-asparagine allyl ester 
• 1182846-84-9 C₅₃H₅₂Cl₃N₃O₁₃ 
• 66963-55-1 1,6-anhydro-2-O-benzoyl-3,4-di-O-benzyl-β-D-glucopyranose 

Relevant articles and documents

Efficient stereoselective synthesis of γ-N-glycosyl asparagines by N-glycosylation of primary amide groups

The efficient and elegant synthesis of N-glycosides by N-glycosylation of asparagine-containing peptides is described. Glycosylation of primary amides with glycosyl N-phenyltrifluoroimidates in the presence of a catalytic amount of TMSOTf in nitromethane

2-Phenyl-tetrahydropyrimidine-4(1H)-ones - Cyclic benzaldehyde aminals as precursors for functionalised β2-amino acids

Novel procedures have been developed to condense benzaldehyde effectively with β-amino acid amides to cyclic benzyl aminals. Double carbamate protection of the heterocycle resulted in fully protected chiral β-alanine derivatives. These serve as universal precursors for the asymmetric synthesis of functionalised β2-amino acids containing acid-labile protected side chains. Diastereoselective alkylation of the tetrahydropyrimidinone is followed by a chemoselective two step degradation of the heterocycle to release the free β2-amino acid. In the course of this study, an L-asparagine derivative was condensed with benzaldehyde and subsequently converted to orthogonally protected (R)-β2-homoaspartate.