7-(3,4-dimethoxyphenyl)-6-(4-methoxyphenyl)-1,2,3,5,8,8a-hexahydroindolizine

Base Information

Chemical Name:7-(3,4-dimethoxyphenyl)-6-(4-methoxyphenyl)-1,2,3,5,8,8a-hexahydroindolizine
CAS No.:184221-13-4
Molecular Formula:C₂₃H₂₇NO₃
Molecular Weight:365.472
Hs Code.:

Synonyms:7-(3,4-dimethoxyphenyl)-6-(4-methoxyphenyl)-1,2,3,5,8,8a-hexahydroindolizine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-(3,4-dimethoxyphenyl)-6-(4-methoxyphenyl)-1,2,3,5,8,8a-hexahydroindolizine

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Technology Process of 7-(3,4-dimethoxyphenyl)-6-(4-methoxyphenyl)-1,2,3,5,8,8a-hexahydroindolizine

There total 41 articles about 7-(3,4-dimethoxyphenyl)-6-(4-methoxyphenyl)-1,2,3,5,8,8a-hexahydroindolizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 7-(3,4-dimethoxyphenyl)-6-(4-methoxyphenyl)-1,2,3,7,8,8a-hexahydroindolizine-5-carbonitrile

: 184221-13-4
7-(3,4-dimethoxyphenyl)-6-(4-methoxyphenyl)-1,2,3,5,8,8a-hexahydroindolizine

Guidance literature:: With sodium tetrahydroborate; isopropyl alcohol; at 100 ℃; for 24h; Sealed tube;
DOI:10.1021/acs.orglett.5b03395

Reference yield: 96.0%

: 7-(3,4-dimethoxyphenyl)-6-(4-methoxyphenyl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one

: 184221-13-4
7-(3,4-dimethoxyphenyl)-6-(4-methoxyphenyl)-1,2,3,5,8,8a-hexahydroindolizine

Guidance literature:: With aluminum (III) chloride; lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 18h;
DOI:10.1002/chem.201702648

Reference yield: 60.0%

: 1236771-00-8
7-(3,4-dimethoxyphenyl)-6-(4-methoxyphenyl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one

: 184221-13-4
7-(3,4-dimethoxyphenyl)-6-(4-methoxyphenyl)-1,2,3,5,8,8a-hexahydroindolizine

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In 1,4-dioxane; toluene; for 2h; Reflux; Inert atmosphere;
DOI:10.1016/j.tet.2010.03.021