(S)-[(5R)-5-{[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxo-2,5-dihydrofuran-3-yl]({2-[(phenylsulfanyl)methyl]phenyl})methyl acetate

Base Information

Chemical Name:(S)-[(5R)-5-{[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxo-2,5-dihydrofuran-3-yl]({2-[(phenylsulfanyl)methyl]phenyl})methyl acetate
CAS No.:1432519-40-8
Molecular Formula:C₃₀H₃₆O₅S
Molecular Weight:508.679
Hs Code.:

Synonyms:(S)-[(5R)-5-{[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxo-2,5-dihydrofuran-3-yl]({2-[(phenylsulfanyl)methyl]phenyl})methyl acetate

Suppliers and Price of (S)-[(5R)-5-{[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxo-2,5-dihydrofuran-3-yl]({2-[(phenylsulfanyl)methyl]phenyl})methyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-[(5R)-5-{[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxo-2,5-dihydrofuran-3-yl]({2-[(phenylsulfanyl)methyl]phenyl})methyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-[(5R)-5-{[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxo-2,5-dihydrofuran-3-yl]({2-[(phenylsulfanyl)methyl]phenyl})methyl acetate

There total 6 articles about (S)-[(5R)-5-{[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxo-2,5-dihydrofuran-3-yl]({2-[(phenylsulfanyl)methyl]phenyl})methyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1432519-39-5
(5R)-3-[(S)-hydroxy({2-[(phenylsulfanyl)methyl]phenyl})methyl]-5-{[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2,5-dihydrofuran-2-one

: 75-36-5
acetyl chloride

: 1432519-40-8
(S)-[(5R)-5-{[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxo-2,5-dihydrofuran-3-yl]({2-[(phenylsulfanyl)methyl]phenyl})methyl acetate

Guidance literature:: With pyridine; dmap; In dichloromethane; at 0 ℃; for 3h; Cooling with ice;
DOI:10.1039/c3ob40115d

Reference yield:

: 87-41-2
2-benzofuran-1(3H)-one

: 1432519-40-8
(S)-[(5R)-5-{[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxo-2,5-dihydrofuran-3-yl]({2-[(phenylsulfanyl)methyl]phenyl})methyl acetate

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydroxide / N,N-dimethyl-formamide

2.1: dimethylsulfide borane complex

3.1: sulfur trioxide pyridine complex; triethylamine / dichloromethane; dimethyl sulfoxide / 12 h / Cooling with ice

4.1: n-butyllithium; diphenyl diselenide / hexane; tetrahydrofuran / 8 h / -45 - -20 °C

4.2: 8 h / -45 - -20 °C

5.1: dmap; pyridine / dichloromethane / 3 h / 0 °C / Cooling with ice

With pyridine; dmap; n-butyllithium; dimethylsulfide borane complex; diphenyl diselenide; sulfur trioxide pyridine complex; triethylamine; sodium hydroxide; In tetrahydrofuran; hexane; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1039/c3ob40115d

Reference yield:

: 108-98-5
thiophenol

: 1432519-40-8
(S)-[(5R)-5-{[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxo-2,5-dihydrofuran-3-yl]({2-[(phenylsulfanyl)methyl]phenyl})methyl acetate

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydroxide / N,N-dimethyl-formamide

2.1: dimethylsulfide borane complex

3.1: sulfur trioxide pyridine complex; triethylamine / dichloromethane; dimethyl sulfoxide / 12 h / Cooling with ice

4.1: n-butyllithium; diphenyl diselenide / hexane; tetrahydrofuran / 8 h / -45 - -20 °C

4.2: 8 h / -45 - -20 °C

5.1: dmap; pyridine / dichloromethane / 3 h / 0 °C / Cooling with ice

With pyridine; dmap; n-butyllithium; dimethylsulfide borane complex; diphenyl diselenide; sulfur trioxide pyridine complex; triethylamine; sodium hydroxide; In tetrahydrofuran; hexane; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1039/c3ob40115d