N-benzoyl-O⁴--L-tyrosine benzyl ester

Base Information

Chemical Name:N-benzoyl-O⁴--L-tyrosine benzyl ester
CAS No.:108572-13-0
Molecular Formula:C₃₇H₃₄NO₆P
Molecular Weight:619.654
Hs Code.:

N-benzoyl-O<sup>4</sup>-<bis(benzyloxy)phosphino>-L-tyrosine benzyl ester

Synonyms:N-benzoyl-O⁴--L-tyrosine benzyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-benzoyl-O⁴--L-tyrosine benzyl ester

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Technology Process of N-benzoyl-O⁴--L-tyrosine benzyl ester

There total 4 articles about N-benzoyl-O⁴--L-tyrosine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 108549-23-1
Dibenzyl N,N-diisopropylphosphoramidite

: 108549-24-2
N-benzoyl tyrosine benzyl ester

: 108572-13-0
N-benzoyl-O⁴--L-tyrosine benzyl ester

Guidance literature:: With 1H-tetrazole; In acetonitrile; for 1h; Ambient temperature;
DOI:10.1002/hlca.19870700122

Reference yield:

: 76101-29-6
benzyloxy dichlorophosphine

: 108572-13-0
N-benzoyl-O⁴--L-tyrosine benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / diethyl ether / 1 h, -10 degC, r.t., overnight

2: 78 percent / diisopropylammonium tetrazolide / CH₂Cl₂ / 2 h

3: 92 percent / tetrazole / acetonitrile / 1 h / Ambient temperature

With 1H-tetrazole; N,N-diisopropylamine tetrazolide; In diethyl ether; dichloromethane; acetonitrile;
DOI:10.1002/hlca.19870700122

Reference yield:

: 108549-21-9
benzyl-N,N,N',N'-tetraisopropylphosphorodiamidite

: 108572-13-0
N-benzoyl-O⁴--L-tyrosine benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / diisopropylammonium tetrazolide / CH₂Cl₂ / 2 h

2: 92 percent / tetrazole / acetonitrile / 1 h / Ambient temperature

With 1H-tetrazole; N,N-diisopropylamine tetrazolide; In dichloromethane; acetonitrile;
DOI:10.1002/hlca.19870700122