1-methyl-d₃-heptyl phenyl ether

Base Information

• Chemical Name: 1-methyl-d₃-heptyl phenyl ether
• CAS No.: 1449563-33-0
• Molecular Formula: C₁₄H₂₂O
• Molecular Weight: 209.304
• Mol file: 1449563-33-0.mol

Synonyms:1-methyl-d₃-heptyl phenyl ether

Chemical Property of 1-methyl-d₃-heptyl phenyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-methyl-d₃-heptyl phenyl ether

There total 2 articles about 1-methyl-d₃-heptyl phenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1,1,1-trideuterio-2-octanol (159754-93-5) + phenol (108-95-2,27073-41-2) → 1-methyl-d3-heptyl phenyl ether (1449563-33-0)

Guidance literature:

1,1,1-trideuterio-2-octanol; phenol; With triphenylphosphine; In tetrahydrofuran; at 0 ℃; for 0.333333h;

With diethylazodicarboxylate; In tetrahydrofuran; at 0 ℃; for 0.333333h;

DOI:10.1021/cs400483q

Reference yield:

heptanal (111-71-7) → 1-methyl-d3-heptyl phenyl ether (1449563-33-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: diethyl ether / 3 h / Reflux

2.1: triphenylphosphine / tetrahydrofuran / 0.33 h / 0 °C

2.2: 0.33 h / 0 °C

With triphenylphosphine; In tetrahydrofuran; diethyl ether;

DOI:10.1021/cs400483q

Reference yield:

1-methyl-d3-heptyl phenyl ether (1449563-33-0) → phenol-d1 (1003-66-3) + octane-1,1-d2 (72089-90-8)

Guidance literature:

With hydrogen; ytterbium(III) triflate; for 18h; under 5171.62 Torr; Ionic liquid; Glovebox;

DOI:10.1021/cs400483q

upstream raw materials:

1,1,1-trideuterio-2-octanol

phenol

heptanal

Downstream raw materials:

phenol-d1

octane-1,1-d₂