6-Hydroxy-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione

Base Information

• Chemical Name: 6-Hydroxy-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
• CAS No.: 23439-87-4
• Molecular Formula: C7H4N2O3
• Molecular Weight: 164.12
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID50546847
• Nikkaji Number: J2.922.338F
• Wikidata: Q72481738
• Mol file: 23439-87-4.mol

Synonyms:23439-87-4;6-Hydroxy-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione;6-HYDROXYPYRROLO[3,4-B]PYRIDINE-5,7-DIONE;5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione, 6-hydroxy-;6-Hydroxy-pyrrolo[3,4-b]pyridine-5,7-dione;N-Hydroxy-2,3-pyridinedicarboximide;SCHEMBL5031312;DTXSID50546847;MFCD11865269;BP-22095;BS-49715;CS-0081576;6-hydroxypyrrolo[3, 4-b]pyridine-5, 7-dione;D74337;A912875

Chemical Property of 6-Hydroxy-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione

Chemical Property:

• Boiling Point: 421.6 °C at 760 mmHg
• PKA: 6.33±0.20(Predicted)
• Flash Point: 208.8 °C
• PSA: 70.50000
• Density: 1.768 g/cm³
• LogP: 0.00470
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 164.02219199
• Heavy Atom Count: 12
• Complexity: 241

Purity/Quality:

97% ^*data from raw suppliers

6-Hydroxypyrrolo[3,4-b]pyridine-5,7-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=O)N(C2=O)O)N=C1

Technology Process of 6-Hydroxy-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione

There total 3 articles about 6-Hydroxy-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.6%

Pyridine-2,3-dicarboxylic anhydride (699-98-9) → 6-hydroxy-5H-pyrrolo[3,4-b]pyridine-5,7-(6H)-dione (23439-87-4)

Guidance literature:

Pyridine-2,3-dicarboxylic anhydride; With hydroxylamine hydrochloride; sodium acetate; In acetic acid; for 0.416667h; Reflux;

In acetic acid;

DOI:10.1002/adsc.201000698

Reference yield:

C7H3N2O3 → 6-hydroxy-5H-pyrrolo[3,4-b]pyridine-5,7-(6H)-dione (23439-87-4)

Guidance literature:

With perchloric acid; Isopropylbenzene; In acetonitrile; at 25 ℃; Reagent/catalyst; Kinetics;

DOI:10.1021/acs.joc.7b00687

Reference yield:

→ 6-hydroxy-5H-pyrrolo[3,4-b]pyridine-5,7-(6H)-dione (23439-87-4)

Guidance literature:

aus (1b) u. SOCl2;

DOI:10.1021/jo00830a046

upstream raw materials:

Pyridine-2,3-dicarboxylic anhydride

Downstream raw materials:

5-p-tolyl-pyrido[3,2-d][1,2]oxazin-8-one

8-p-tolyl-pyrido[2,3-d][1,2]oxazin-5-one

3-Hydroxypyrido<3,2-d>pyrimidin-2,4(1H,3H)dion

3-[3-(4-Methoxy-phenyl)-ureido]-pyridine-2-carboxylic acid (4-methoxy-phenyl)-amide