Technology Process of 3,6-dimethyl-2-phenethylpyridine
There total 2 articles about 3,6-dimethyl-2-phenethylpyridine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
methyl vinyl ketone; 4-methyl-1-phenyl-hex-5-en-3-ol;
With
1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene[2-(iso-propoxy)-5-(N,N-dimethylaminosulfonyl)phenyl]methylene ruthenium(II) dichloride;
In
dichloromethane;
at 55 ℃;
for 24h;
Inert atmosphere;
With
water; Dess-Martin periodane;
In
dichloromethane;
at 0 ℃;
With
ammonium acetate; acetic acid;
In
ethanol;
at 55 ℃;
for 24h;
DOI:10.1021/ol103088r
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: ammonium chloride; zinc / tetrahydrofuran; water / 20 °C
2.1: 1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene[2-(iso-propoxy)-5-(N,N-dimethylaminosulfonyl)phenyl]methylene ruthenium(II) dichloride / dichloromethane / 24 h / 55 °C / Inert atmosphere
2.2: 0 °C
2.3: 24 h / 55 °C
With
1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene[2-(iso-propoxy)-5-(N,N-dimethylaminosulfonyl)phenyl]methylene ruthenium(II) dichloride; ammonium chloride; zinc;
In
tetrahydrofuran; dichloromethane; water;
2.1: Olefin cross-metathesis / 2.2: Dess-Martin oxidation;
DOI:10.1021/ol103088r
