N-(1-adamantyl)methyl-4-fluoro-N'-[2-(n-morpholino)ethyl]-1,2-phenylenediamine

Base Information

Chemical Name:N-(1-adamantyl)methyl-4-fluoro-N'-[2-(n-morpholino)ethyl]-1,2-phenylenediamine
CAS No.:163618-43-7
Molecular Formula:C₂₃H₃₄FN₃O
Molecular Weight:387.541
Hs Code.:

Synonyms:N-(1-adamantyl)methyl-4-fluoro-N'-[2-(n-morpholino)ethyl]-1,2-phenylenediamine

Suppliers and Price of N-(1-adamantyl)methyl-4-fluoro-N'-[2-(n-morpholino)ethyl]-1,2-phenylenediamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(1-adamantyl)methyl-4-fluoro-N'-[2-(n-morpholino)ethyl]-1,2-phenylenediamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(1-adamantyl)methyl-4-fluoro-N'-[2-(n-morpholino)ethyl]-1,2-phenylenediamine

There total 6 articles about N-(1-adamantyl)methyl-4-fluoro-N'-[2-(n-morpholino)ethyl]-1,2-phenylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.5%

: 163618-07-3
N-(1-adamantanecarbonyl)-4-fluoro-N'-[2-(morpholin-4-yl)ethyl]-1,2-phenylenediamine

: 163618-43-7
N-(1-adamantyl)methyl-4-fluoro-N'-[2-(n-morpholino)ethyl]-1,2-phenylenediamine

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; at 0 - 23 ℃; for 0.666667h;
DOI:10.1016/j.bmc.2011.05.057

Reference yield:

: 2038-03-1
4-(2-AMINOETHYL)MORPHOLINE

: 163618-43-7
N-(1-adamantyl)methyl-4-fluoro-N'-[2-(n-morpholino)ethyl]-1,2-phenylenediamine

Guidance literature:: Multi-step reaction with 4 steps

1.1: tetrahydrofuran / 24 h / 23 °C

2.1: sodium dithionite; water; potassium carbonate / ethanol / 0.5 h / 23 °C

2.2: pH 3

2.3: pH 10

3.1: triethylamine / tetrahydrofuran / 1.5 h / 60 °C

4.1: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / 0.67 h / 0 - 23 °C

With sodium dithionite; water; potassium carbonate; triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; ethanol; toluene;
DOI:10.1016/j.bmc.2011.05.057

Reference yield:

: 163618-06-2
5-fluoro-N₁-[2-(morpholin-4-yl)ethyl]-1,2-phenylenediamine

: 163618-43-7
N-(1-adamantyl)methyl-4-fluoro-N'-[2-(n-morpholino)ethyl]-1,2-phenylenediamine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 1.5 h / 60 °C

2: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / 0.67 h / 0 - 23 °C

With triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; toluene;
DOI:10.1016/j.bmc.2011.05.057