N-Benzyl-3-methylazacycloheptane

Base Information

• Chemical Name: N-Benzyl-3-methylazacycloheptane
• CAS No.: 78805-13-7
• Molecular Formula: C₁₄H₂₁N
• Molecular Weight: 203.327
• Mol file: 78805-13-7.mol

Synonyms:N-Benzyl-3-methylazacycloheptane

Chemical Property of N-Benzyl-3-methylazacycloheptane

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-Benzyl-3-methylazacycloheptane

There total 3 articles about N-Benzyl-3-methylazacycloheptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

carbon monoxide (201230-82-2) + N,N-di-2-propenylbenzylamine (4383-26-0) → N-benzylpyrrolidine (29897-82-3) + 3-methyl-1-phenylmethylpyrrole (78075-81-7) + N-Benzyl-3-methylazacycloheptane (78805-13-7)

Guidance literature:

With hydrogen; carbonylhydridetris(triphenylphosphine)rhodium(I); In benzene; at 90 ℃; for 5h; under 72400.7 Torr;

DOI:10.1021/jo00335a022

Reference yield: 6.0%

N,N-di-2-propenylbenzylamine (4383-26-0) → N-benzylpyrrolidine (29897-82-3) + 3-methyl-1-phenylmethylpyrrole (78075-81-7) + N-Benzyl-3-methylazacycloheptane (78805-13-7)

Guidance literature:

With carbon monoxide; hydrogen; carbonylhydridetris(triphenylphosphine)rhodium(I); In benzene; at 90 ℃; for 5h; under 72400.7 Torr;

DOI:10.1021/jo00335a022

Reference yield:

Hexahydro-N-benzyl-3-methyl-2H-azepin-2-one (37672-45-0) → N-Benzyl-3-methylazacycloheptane (78805-13-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 15h; Heating;

DOI:10.1021/jo00335a022

upstream raw materials:

Hexahydro-N-benzyl-3-methyl-2H-azepin-2-one

carbon monoxide

N,N-di-2-propenylbenzylamine