4-Nitro-benzoic acid (1R,2R,3R,5R)-3-(tert-butyl-diphenyl-silanyloxy)-5-methoxycarbonyl-2-methyl-cyclohexyl ester

Base Information

Chemical Name:4-Nitro-benzoic acid (1R,2R,3R,5R)-3-(tert-butyl-diphenyl-silanyloxy)-5-methoxycarbonyl-2-methyl-cyclohexyl ester
CAS No.:758719-45-8
Molecular Formula:C₃₂H₃₇NO₇Si
Molecular Weight:575.734
Hs Code.:

Synonyms:4-Nitro-benzoic acid (1R,2R,3R,5R)-3-(tert-butyl-diphenyl-silanyloxy)-5-methoxycarbonyl-2-methyl-cyclohexyl ester

Suppliers and Price of 4-Nitro-benzoic acid (1R,2R,3R,5R)-3-(tert-butyl-diphenyl-silanyloxy)-5-methoxycarbonyl-2-methyl-cyclohexyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Nitro-benzoic acid (1R,2R,3R,5R)-3-(tert-butyl-diphenyl-silanyloxy)-5-methoxycarbonyl-2-methyl-cyclohexyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Nitro-benzoic acid (1R,2R,3R,5R)-3-(tert-butyl-diphenyl-silanyloxy)-5-methoxycarbonyl-2-methyl-cyclohexyl ester

There total 5 articles about 4-Nitro-benzoic acid (1R,2R,3R,5R)-3-(tert-butyl-diphenyl-silanyloxy)-5-methoxycarbonyl-2-methyl-cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 758719-39-0
methyl (1R,3S,4R,5R)-5-(tert-butyldiphenylsilyloxy)-3-hydroxy-4-methylcyclohexane-1-carboxylate

: 62-23-7
4-nitro-benzoic acid

: 758719-45-8
4-Nitro-benzoic acid (1R,2R,3R,5R)-3-(tert-butyl-diphenyl-silanyloxy)-5-methoxycarbonyl-2-methyl-cyclohexyl ester

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.1002/ejoc.200500289

Reference yield:

: 757240-15-6
(1R,5R)-5-Hydroxy-4-methyl-cyclohex-3-enecarboxylic acid methyl ester

: 758719-45-8
4-Nitro-benzoic acid (1R,2R,3R,5R)-3-(tert-butyl-diphenyl-silanyloxy)-5-methoxycarbonyl-2-methyl-cyclohexyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 1.68 g / imidazole; DMAP / dimethylformamide / 10 h / 20 °C

2.1: BH₃ / tetrahydrofuran / 2.5 h / 0 °C

2.2: 35 percent / H₂O₂; NaHCO₃ / tetrahydrofuran / 0.5 h

3.1: 81 percent / PPh₃; DIAD / tetrahydrofuran / 24 h / 20 °C

With 1H-imidazole; dmap; di-isopropyl azodicarboxylate; borane; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide; 3.1: Mitsunobu inversion;
DOI:10.1002/ejoc.200500289

Reference yield:

: 758719-38-9
methyl (1R,5R)-5-(tert-butyldiphenylsilyloxy)-4-methyl-3-cyclohexene-1-carboxylate

: 758719-45-8
4-Nitro-benzoic acid (1R,2R,3R,5R)-3-(tert-butyl-diphenyl-silanyloxy)-5-methoxycarbonyl-2-methyl-cyclohexyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: BH₃ / tetrahydrofuran / 2.5 h / 0 °C

1.2: 35 percent / H₂O₂; NaHCO₃ / tetrahydrofuran / 0.5 h

2.1: 81 percent / PPh₃; DIAD / tetrahydrofuran / 24 h / 20 °C

With di-isopropyl azodicarboxylate; borane; triphenylphosphine; In tetrahydrofuran; 2.1: Mitsunobu inversion;
DOI:10.1002/ejoc.200500289