cyclo[Pro(4-OCO-NH-CH₂-CH₂-NH-Boc)-Phg-D-Trp(BoC)-Lys(Boc)-Tyr(Bzl)-Phe]

Base Information

Chemical Name:cyclo[Pro(4-OCO-NH-CH₂-CH₂-NH-Boc)-Phg-D-Trp(BoC)-Lys(Boc)-Tyr(Bzl)-Phe]
CAS No.:842149-91-1
Molecular Formula:C₇₃H₉₀N₁₀O₁₅
Molecular Weight:1347.58
Hs Code.:

cyclo[Pro(4-OCO-NH-CH<sub>2</sub>-CH<sub>2</sub>-NH-Boc)-Phg-D-Trp(BoC)-Lys(Boc)-Tyr(Bzl)-Phe]

Synonyms:cyclo[Pro(4-OCO-NH-CH₂-CH₂-NH-Boc)-Phg-D-Trp(BoC)-Lys(Boc)-Tyr(Bzl)-Phe]

Suppliers and Price of cyclo[Pro(4-OCO-NH-CH₂-CH₂-NH-Boc)-Phg-D-Trp(BoC)-Lys(Boc)-Tyr(Bzl)-Phe]

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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price

Total 2 raw suppliers

Chemical Property of cyclo[Pro(4-OCO-NH-CH₂-CH₂-NH-Boc)-Phg-D-Trp(BoC)-Lys(Boc)-Tyr(Bzl)-Phe]

Chemical Property:

Purity/Quality:: ≥95% ^*data from raw suppliers

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Hazard Codes:

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Technology Process of cyclo[Pro(4-OCO-NH-CH₂-CH₂-NH-Boc)-Phg-D-Trp(BoC)-Lys(Boc)-Tyr(Bzl)-Phe]

There total 2 articles about cyclo[Pro(4-OCO-NH-CH₂-CH₂-NH-Boc)-Phg-D-Trp(BoC)-Lys(Boc)-Tyr(Bzl)-Phe] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57260-73-8
N-BOC-1,2-diaminoethane

: cyclo(Phe-Pro(4-OH)-Phg-D-Trp(Boc)-Lys(Boc)-Tyr(Bzl))

: 530-62-1
1,1'-carbonyldiimidazole

: 842149-91-1
cyclo[Pro(4-OCO-NH-CH₂-CH₂-NH-Boc)-Phg-D-Trp(BoC)-Lys(Boc)-Tyr(Bzl)-Phe]

Guidance literature:: cyclo(Phe-Pro(4-OH)-Phg-D-Trp(Boc)-Lys(Boc)-Tyr(Bzl)); 1,1'-carbonyldiimidazole; With dmap; In dichloromethane; at 0 - 20 ℃; for 1h;

N-BOC-1,2-diaminoethane; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 25 ℃; for 12h;

Reference yield:

: 396091-74-0
H-Phe-(2S,4R)-(4-OCO-NH-CH₂-CH₂-NH-Boc)-Pro-Phg-D-Trp(Boc)-Lys(Boc)-Tyr(Bzl)-OH

: 842149-91-1
cyclo[Pro(4-OCO-NH-CH₂-CH₂-NH-Boc)-Phg-D-Trp(BoC)-Lys(Boc)-Tyr(Bzl)-Phe]

Guidance literature:: With diphenyl-phosphinic acid; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at -5 - 4 ℃; for 20h;
DOI:10.1021/jm021093t