C₄₅H₄₀I₂Si

Base Information

• Chemical Name: C₄₅H₄₀I₂Si
• CAS No.: 1404213-46-2
• Molecular Formula: C₄₅H₄₀I₂Si
• Molecular Weight: 862.707
• Mol file: 1404213-46-2.mol

Synonyms:C₄₅H₄₀I₂Si

Chemical Property of C₄₅H₄₀I₂Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₅H₄₀I₂Si

There total 3 articles about C₄₅H₄₀I₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromo-3,5-diiodobenzene (149428-64-8) → C45H40I2Si (1404213-46-2)

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 20 °C

2: copper(l) iodide; triphenylphosphine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / triethylamine / 48 h / 60 °C / Inert atmosphere

3: potassium hydroxide / methanol; tetrahydrofuran / 1 h

4: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; copper(l) iodide; triethylamine; N-ethyl-N,N-diisopropylamine; triphenylphosphine; potassium hydroxide; In tetrahydrofuran; methanol; triethylamine; 1: |Sonogashira Cross-Coupling / 2: |Sonogashira Cross-Coupling / 4: |Sonogashira Cross-Coupling;

DOI:10.1002/ejoc.201200655

Reference yield:

(5-bromo-1,3-phenylene)bis(ethyne-2,1-diyl)bis(trimethylsilane) (144001-09-2) → C45H40I2Si (1404213-46-2)

Guidance literature:

Multi-step reaction with 3 steps

1: copper(l) iodide; triphenylphosphine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / triethylamine / 48 h / 60 °C / Inert atmosphere

2: potassium hydroxide / methanol; tetrahydrofuran / 1 h

3: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; copper(l) iodide; N-ethyl-N,N-diisopropylamine; triphenylphosphine; potassium hydroxide; In tetrahydrofuran; methanol; triethylamine; 1: |Sonogashira Cross-Coupling / 3: |Sonogashira Cross-Coupling;

DOI:10.1002/ejoc.201200655

Reference yield:

1-(triisopropylsilylethynyl)-3,5-bis(trimethylsilylethynyl)benzene (223799-08-4) → C45H40I2Si (1404213-46-2)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / methanol; tetrahydrofuran / 1 h

2: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine; potassium hydroxide; In tetrahydrofuran; methanol; 2: |Sonogashira Cross-Coupling;

DOI:10.1002/ejoc.201200655

upstream raw materials:

1-bromo-3,5-diiodobenzene

(5-bromo-1,3-phenylene)bis(ethyne-2,1-diyl)bis(trimethylsilane)

1-(triisopropylsilylethynyl)-3,5-bis(trimethylsilylethynyl)benzene

Downstream raw materials:

C₇₇H₈₂O₂Si