3-(5-methyl-3-phenylisoxazol-4-yl)-8-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-5H-[1,2,4]triazolo[3,4-a]isoindole

Base Information

Chemical Name:3-(5-methyl-3-phenylisoxazol-4-yl)-8-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-5H-[1,2,4]triazolo[3,4-a]isoindole
CAS No.:675109-71-4
Molecular Formula:C₂₅H₂₃N₅O
Molecular Weight:409.491
Hs Code.:

Synonyms:3-(5-methyl-3-phenylisoxazol-4-yl)-8-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-5H-[1,2,4]triazolo[3,4-a]isoindole

Suppliers and Price of 3-(5-methyl-3-phenylisoxazol-4-yl)-8-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-5H-[1,2,4]triazolo[3,4-a]isoindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(5-methyl-3-phenylisoxazol-4-yl)-8-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-5H-[1,2,4]triazolo[3,4-a]isoindole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(5-methyl-3-phenylisoxazol-4-yl)-8-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-5H-[1,2,4]triazolo[3,4-a]isoindole

There total 5 articles about 3-(5-methyl-3-phenylisoxazol-4-yl)-8-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-5H-[1,2,4]triazolo[3,4-a]isoindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3-(5-methyl-3-phenylisoxazol-4-yl)-8-(1,2,3,6-tetrahydropyridin-4-yl)-5H-[1,2,4]triazolo[3,4-a]isoindole

: 675109-71-4
3-(5-methyl-3-phenylisoxazol-4-yl)-8-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-5H-[1,2,4]triazolo[3,4-a]isoindole

Guidance literature:: With formaldehyd; sodium cyanotrihydroborate; nitrogen; In methanol; at 20 ℃; for 3h;

Reference yield:

: 675109-51-0
5-methyl-3-phenylisoxazole-4-carboxylic acid N'-(6-iodo-3H-isoindol-1-yl)-hydrazide

: 675109-71-4
3-(5-methyl-3-phenylisoxazol-4-yl)-8-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-5H-[1,2,4]triazolo[3,4-a]isoindole

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid

2.1: nitrogen / DMF (N,N-dimethyl-formamide) / 1 h

2.2: 8 h / 100 °C

3.1: trifluoroacetic acid / 0.5 h / 20 °C

4.1: formaldehyd; sodium cyanotrihydroborate; nitrogen / methanol / 3 h / 20 °C

With formaldehyd; sodium cyanotrihydroborate; nitrogen; In methanol; DMF (N,N-dimethyl-formamide); acetic acid; trifluoroacetic acid;

Reference yield:

: 4-[3-(5-methyl-3-phenylisoxazol-4-yl)-5H-[1,2,4]triazolo[3,4-a]isoindol-8-yl]-3,6-dihydro-2H-pyridine-1-carboxylic Acid Tert-Butyl Ester

: 675109-71-4
3-(5-methyl-3-phenylisoxazol-4-yl)-8-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-5H-[1,2,4]triazolo[3,4-a]isoindole

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / 0.5 h / 20 °C

2: formaldehyd; sodium cyanotrihydroborate; nitrogen / methanol / 3 h / 20 °C

With formaldehyd; sodium cyanotrihydroborate; nitrogen; In methanol; trifluoroacetic acid;