4-Amino-3-chloropyridin-2-ol

Base Information

Chemical Name:4-Amino-3-chloropyridin-2-ol
CAS No.:55290-73-8
Molecular Formula:C5H5ClN2O
Molecular Weight:144.56
Hs Code.:2933399990
DSSTox Substance ID:DTXSID40552432
Wikidata:Q82432674
Mol file:55290-73-8.mol

Synonyms:4-Amino-3-chloropyridin-2-ol;55290-73-8;4-Amino-3-chloro-2-hydroxypyridine;4-amino-3-chloro-1H-pyridin-2-one;4-Amino-3-chloropyridin-2(1H)-one;MFCD09763693;SCHEMBL10601219;DTXSID40552432;AKOS006337416;AKOS015891606;AB51578;CS-W004453;AS-77091;SY121221;D97574;A830577

Suppliers and Price of 4-Amino-3-chloropyridin-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Amino-3-chloropyridin-2-ol 95+%
1g
$ 510.00

Chemenu
4-Amino-3-chloropyridin-2-ol 95%
1g
$ 482.00

Chemcia Scientific
4-Amino-3-chloro-pyridin-2-ol 95%
5 G
$ 1385.00

American Custom Chemicals Corporation
4-AMINO-3-CHLORO-2-HYDROXYPYRIDINE 95.00%
5G
$ 909.56

Alichem
4-Amino-3-chloro-2-hydroxypyridine
500mg
$ 960.40

Alichem
4-Amino-3-chloro-2-hydroxypyridine
250mg
$ 700.40

Activate Scientific
4-Amino-3-chloropyridin-2-ol 97%
1 g
$ 503.00

Total 19 raw suppliers

Chemical Property of 4-Amino-3-chloropyridin-2-ol

Chemical Property:

Vapor Pressure:0.00725mmHg at 25°C
Melting Point:164-167 °C
Refractive Index:1.615
Boiling Point:269.4 °C at 760 mmHg
PKA:10.00±0.10(Predicted)
Flash Point:116.8 °C
PSA：59.14000
Density:1.45 g/cm³
LogP:1.60400
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:144.0090405
Heavy Atom Count:9
Complexity:207

Purity/Quality:

98%min ^*data from raw suppliers

4-Amino-3-chloropyridin-2-ol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CNC(=O)C(=C1N)Cl

Technology Process of 4-Amino-3-chloropyridin-2-ol

There total 3 articles about 4-Amino-3-chloropyridin-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 38767-72-5
3-deazaC

: 55290-73-8
4-amino-3-chloro-2(1H)-pyridinone

Guidance literature:: With N-chloro-succinimide; In acetic acid; for 2h;
DOI:10.1021/jm00169a032

Reference yield: 60.0%

: 3-chloro-2-methoxypyridin-4-ylamine

: 55290-73-8
4-amino-3-chloro-2(1H)-pyridinone

Guidance literature:: With boron tribromide; In 1,2-dichloro-ethane; at 0 - 80 ℃; for 12h;

Reference yield:

: 20265-39-8
4-amino-2-methoxypyridine

: 55290-73-8
4-amino-3-chloro-2(1H)-pyridinone

Guidance literature:: Multi-step reaction with 2 steps

1: N-chloro-succinimide / N,N-dimethyl-formamide / 36 h / 15 - 30 °C / Inert atmosphere

2: boron tribromide / 1,2-dichloro-ethane / 12 h / 0 - 80 °C

With N-chloro-succinimide; boron tribromide; In 1,2-dichloro-ethane; N,N-dimethyl-formamide;