ethyl 3-(2-ethyl-4-{2-[2-(4-fluorophenyl)-5-methyloxazol-4-yl]ethoxy} phenyl)propionate

Base Information

Chemical Name:ethyl 3-(2-ethyl-4-{2-[2-(4-fluorophenyl)-5-methyloxazol-4-yl]ethoxy} phenyl)propionate
CAS No.:1352086-04-4
Molecular Formula:C₂₅H₂₈FNO₄
Molecular Weight:425.5
Hs Code.:

Synonyms:ethyl 3-(2-ethyl-4-{2-[2-(4-fluorophenyl)-5-methyloxazol-4-yl]ethoxy} phenyl)propionate

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Chemical Property of ethyl 3-(2-ethyl-4-{2-[2-(4-fluorophenyl)-5-methyloxazol-4-yl]ethoxy} phenyl)propionate

Chemical Property:

Purity/Quality:

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Technology Process of ethyl 3-(2-ethyl-4-{2-[2-(4-fluorophenyl)-5-methyloxazol-4-yl]ethoxy} phenyl)propionate

There total 9 articles about ethyl 3-(2-ethyl-4-{2-[2-(4-fluorophenyl)-5-methyloxazol-4-yl]ethoxy} phenyl)propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 729590-46-9
3-(2-ethyl-4-hydroxyphenyl)propionic acid ethyl ester

: 477541-31-4
2-[2-(4-fluorophenyl)-5-methyloxazol-4-yl]ethyl methanesulfonate

: 1352086-04-4
ethyl 3-(2-ethyl-4-{2-[2-(4-fluorophenyl)-5-methyloxazol-4-yl]ethoxy} phenyl)propionate

Guidance literature:: With potassium carbonate; In acetonitrile; for 16h; Reflux;

Reference yield:

: 1352085-98-3
3-bromo-4-carbonylpentyl benzoate

: 1352086-04-4
ethyl 3-(2-ethyl-4-{2-[2-(4-fluorophenyl)-5-methyloxazol-4-yl]ethoxy} phenyl)propionate

Guidance literature:: Multi-step reaction with 7 steps

1: sodium azide / N,N-dimethyl-formamide / 20 °C

2: hydrogen; palladium on activated charcoal / methanol

3: potassium carbonate / ethyl acetate / 0 - 5 °C

4: trichlorophosphate / toluene / 2.5 h / 20 °C / Reflux

5: sodium hydroxide; water / ethanol / 20 °C

6: triethylamine / dichloromethane / 0 - 20 °C

7: potassium carbonate / acetonitrile / 16 h / Reflux

With sodium azide; palladium on activated charcoal; water; hydrogen; potassium carbonate; triethylamine; sodium hydroxide; trichlorophosphate; In methanol; ethanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; toluene; acetonitrile;

Reference yield:

: 1352085-99-4
3-azido-4-carbonylpentyl benzoate

: 1352086-04-4
ethyl 3-(2-ethyl-4-{2-[2-(4-fluorophenyl)-5-methyloxazol-4-yl]ethoxy} phenyl)propionate

Guidance literature:: Multi-step reaction with 6 steps

1: hydrogen; palladium on activated charcoal / methanol

2: potassium carbonate / ethyl acetate / 0 - 5 °C

3: trichlorophosphate / toluene / 2.5 h / 20 °C / Reflux

4: sodium hydroxide; water / ethanol / 20 °C

5: triethylamine / dichloromethane / 0 - 20 °C

6: potassium carbonate / acetonitrile / 16 h / Reflux

With palladium on activated charcoal; water; hydrogen; potassium carbonate; triethylamine; sodium hydroxide; trichlorophosphate; In methanol; ethanol; dichloromethane; ethyl acetate; toluene; acetonitrile;