4-Bromo-2-hydroxypyridine

Base Information

Chemical Name:4-Bromo-2-hydroxypyridine
CAS No.:36953-37-4
Molecular Formula:C5H4BrNO
Molecular Weight:173.997
Hs Code.:29333990
European Community (EC) Number:640-429-6
DSSTox Substance ID:DTXSID00355749
Nikkaji Number:J3.479.549E
Wikidata:Q72457002
Mol file:36953-37-4.mol

Synonyms:4-bromopyridone

Suppliers and Price of 4-Bromo-2-hydroxypyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Bromo-2-hydroxypyridine
25g
$ 580.00

TRC
4-Bromo-2-hydroxypyridine
2.5g
$ 120.00

TCI Chemical
4-Bromo-2-hydroxypyridine >98.0%(GC)(T)
1g
$ 160.00

SynQuest Laboratories
4-Bromo-1H-pyridin-2-one
25 g
$ 192.00

SynQuest Laboratories
4-Bromo-1H-pyridin-2-one
1 g
$ 16.00

SynQuest Laboratories
4-Bromo-1H-pyridin-2-one
5 g
$ 45.00

Matrix Scientific
4-Bromo-2(1H)-pyridinone 97.0%
1g
$ 66.00

Labseeker
4-Bromo-2-hydroxypyridine 95
25g
$ 431.00

J&W Pharmlab
4-Bromo-pyridin-2-ol 97%
25g
$ 398.00

Crysdot
4-Bromopyridin-2-ol 97%
100g
$ 396.00

Total 113 raw suppliers

Chemical Property of 4-Bromo-2-hydroxypyridine

Chemical Property:

Vapor Pressure:0.418mmHg at 25°C
Melting Point:186 °C
Refractive Index:1.543
Boiling Point:305.9 °C at 760 mmHg
PKA:10.54±0.10(Predicted)
Flash Point:138.8 °C
PSA：33.12000
Density:1.776 g/cm³
LogP:1.54970
Storage Temp.:Room temperature.
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:172.94763
Heavy Atom Count:8
Complexity:171

Purity/Quality:

99% ^*data from raw suppliers

4-Bromo-2-hydroxypyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/38
Safety Statements: 36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CNC(=O)C=C1Br
Uses 4-Bromo-2-hydroxypyridine is used as a reagent to synthesize trans-3,4’-bispyridinylethylenes, compounds that act as inhibitors of protein kinase B that are used to treat cancer.

Technology Process of 4-Bromo-2-hydroxypyridine

There total 6 articles about 4-Bromo-2-hydroxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 100367-39-3
4-bromo-2-methoxypyridine

: 36953-37-4
4-bromo-2(1H)-pyridinone

Guidance literature:: 4-bromo-2-methoxypyridine; With hydrogenchloride; water; In 1,4-dioxane; at 50 - 90 ℃;

With sodium hydroxide; In 1,4-dioxane; water; pH=8 - 9;

Reference yield: 86.0%

: 73583-37-6
2-chloro-4-bromopyridine

: 36953-37-4
4-bromo-2(1H)-pyridinone

Guidance literature:: 2-chloro-4-bromopyridine; With potassium tert-butylate; In tert-Amyl alcohol; at 80 ℃; for 16h; Schlenk technique; Inert atmosphere;

With formic acid; at 20 ℃; for 24h;
DOI:10.1055/s-0034-1378703