1-Methyl-1,8-naphthyridin-2(1H)-one

Base Information

Chemical Name:1-Methyl-1,8-naphthyridin-2(1H)-one
CAS No.:15936-11-5
Molecular Formula:C₉H₈N₂O
Molecular Weight:160.175
Hs Code.:2933990090
DSSTox Substance ID:DTXSID20541546
Wikidata:Q82417924
Mol file:15936-11-5.mol

Synonyms:15936-11-5;1-METHYL-1,8-NAPHTHYRIDIN-2-ONE;1-METHYL-1,8-NAPHTHYRIDIN-2(1H)-ONE;1,8-Naphthyridin-2(1H)-one,1-methyl-(8CI,9CI);1,8-Naphthyridin-2(1H)-one,1-methyl-;SCHEMBL2614748;DTXSID20541546;AKOS015911478

Suppliers and Price of 1-Methyl-1,8-naphthyridin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-Methyl-1,8-naphthyridin-2(1H)-one

Chemical Property:

PSA：34.89000
LogP:0.93350
XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:160.063662883
Heavy Atom Count:12
Complexity:225

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=O)C=CC2=C1N=CC=C2

Technology Process of 1-Methyl-1,8-naphthyridin-2(1H)-one

There total 4 articles about 1-Methyl-1,8-naphthyridin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 37960-59-1
1-methyl-1,8-naphthyridinium iodide

: 15936-11-5
1,2-dihydro-1-methyl-1,8-naphthyridin-2-one

Guidance literature:: With Eosin Y; caesium carbonate; In tetrahydrofuran; at 25 ℃; for 10h; Irradiation; Green chemistry;
DOI:10.1021/jacs.7b07883

Reference yield: 3.0%

: 37960-59-1
1-methyl-1,8-naphthyridinium iodide

: 103976-52-9
2-(methylamino)pyridine-3-carboxamide

: 103976-51-8
1,2-dihydro-2-imino-methyl-1,8-naphthyridine hydroiodide

: 15936-11-5
1,2-dihydro-1-methyl-1,8-naphthyridin-2-one

Guidance literature:: With potassium permanganate; ammonia; Yield given. Multistep reaction; 1.) 20 min, 2.) water;

Reference yield:

: 103976-54-1
2-amino-1,2-dihydro-1-methyl-1,8-naphthyridine

: 15936-11-5
1,2-dihydro-1-methyl-1,8-naphthyridin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium permanganate / liquid ammonia

2: aq.potassium hydroxide (10 percent) / 4 h / Heating

With potassium hydroxide; potassium permanganate; In ammonia;